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Titolo:
Purinergic signalling: ATP release
Autore:
Bodin, P; Burnstock, G;
Indirizzi:
Univ Coll London, Royal Free & Univ Coll Sch Med, Auton Neurosci Inst, London NW3 2PF, England Univ Coll London London England NW3 2PF ci Inst, London NW3 2PF, England
Titolo Testata:
NEUROCHEMICAL RESEARCH
fascicolo: 8-9, volume: 26, anno: 2001,
pagine: 959 - 969
SICI:
0364-3190(200109)26:8-9<959:PSAR>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSMEMBRANE CONDUCTANCE REGULATOR; PIG VAS-DEFERENS; DEPOLARIZATION-INDUCED RELEASE; VASCULAR ENDOTHELIAL-CELLS; MOTOR-NERVE TERMINALS; SMOOTH-MUSCLE CELLS; ADENOSINE-TRIPHOSPHATE; SYNAPTIC TRANSMISSION; ADENINE-NUCLEOTIDES; EPITHELIAL-CELLS;
Keywords:
adenosine triphosphate; exocytosis; ATP binding cassette proteins; purinoceptors; neurotransmitter;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
129
Recensione:
Indirizzi per estratti:
Indirizzo: Burnstock, G Univ Coll London, Royal Free & Univ Coll Sch Med, Auton Neurosci Inst, Royal Free Campus,Rowland Hill St, London NW3 2PF, England Univ Coll London Royal Free Campus,Rowland Hill St London England NW3 2PF
Citazione:
P. Bodin e G. Burnstock, "Purinergic signalling: ATP release", NEUROCHEM R, 26(8-9), 2001, pp. 959-969

Abstract

Adenosine triphosphate (ATP) has a fundamental intracellular role as the universal source of energy for all living cells. The demonstration of its release into the extracellular space and the identification and localisation of specific receptors on target cells have been essential in establishing, after considerable resistance, its extracellular physiological roles. It isnow generally accepted that ATP is a genuine neurotransmitter both in the central and peripheral nervous Systems. As such, there are numerous arguments which prove that the release of ATP by nerve terminals is by exocytosis. In some non-neuronal cells, however, recent evidence suggests that ATP release could also be carrier-mediated and would involve ATP-binding cassette proteins (ABC), an ubiquitous family of transport ATPases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 12:21:44