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Titolo:
Li-7 2D CSI of human brain on a clinical scanner
Autore:
Girard, F; Suhara, T; Sassa, T; Okubo, Y; Obata, T; Ikehira, H; Sudo, Y; Koga, M; Yoshioka, H; Yoshida, K;
Indirizzi:
Natl Inst Radiol Sci, Div Med Imaging, Chiba 260, Japan Natl Inst Radiol Sci Chiba Japan 260 , Div Med Imaging, Chiba 260, Japan Japan Sci & Technol Corp, CREST, Tokyo, Japan Japan Sci & Technol Corp Tokyo Japan Technol Corp, CREST, Tokyo, Japan Tokyo Med & Dent Univ, Fac Med, Dept Neuropsychiat, Tokyo 113, Japan TokyoMed & Dent Univ Tokyo Japan 113 pt Neuropsychiat, Tokyo 113, Japan
Titolo Testata:
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
fascicolo: 1, volume: 13, anno: 2001,
pagine: 1 - 7
SICI:
0968-5243(200108)13:1<1:L2COHB>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE SPECTROSCOPY; LITHIUM CONCENTRATION; IN-VIVO; 2ND MESSENGERS; RELAXATION; TISSUE;
Keywords:
MR imaging; lithium-7; psychiatry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Girard, F Univ Zurich Hosp, Dept Magnet Resonance, GE Med Syst, Ramistr 100, CH-8091Zurich, Switzerland Univ Zurich Hosp Ramistr 100 Zurich Switzerland CH-8091 zerland
Citazione:
F. Girard et al., "Li-7 2D CSI of human brain on a clinical scanner", MAGN RES MA, 13(1), 2001, pp. 1-7

Abstract

Lithium salts have been widely used in the treatment of mood disorders, but the mechanism of action is still not clear. In this work, a methodology for two-dimensional Lithium-7 imaging on clinical systems is presented. The data were acquired using a phosphorus volume head coil that was re-tuned for the Lithium-7 frequency. A spectroscopic sequence was used to acquire thefree induction decay (FID) after volume excitation using a hard pulse. Theresults obtained on the head of patients undergoing lithium treatment (n=7, 0.6 mEq/l average serum level) demonstrate that images of adequate signalto noise ratio (100:1) can be obtained in acceptable imaging times (55 min) using the proposed methodology. The distribution of Li-7 appears uniform in the brains of the patients studied. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 09:30:11