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Titolo:
Independent effects of residual renal function and dialysis adequacy on actual dietary protein, calorie, and other nutrient intake in patients on continuous ambulatory peritoneal dialysis
Autore:
Wang, AYM; Sea, MMM; Ip, R; Law, MC; Chow, KM; Lui, SF; Li, PKT; Woo, J;
Indirizzi:
Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Ctr Nutr Studies, Shatin, Hong Kong, Peoples R China Chinese Univ Hong Kong Shatin Hong Kong Peoples R China Peoples R China
Titolo Testata:
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
fascicolo: 11, volume: 12, anno: 2001,
pagine: 2450 - 2457
SICI:
1046-6673(200111)12:11<2450:IEORRF>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAPD PATIENTS; CATABOLIC RATE; TASTE ACUITY; MORTALITY; KT/V; MORBIDITY; NUTRITION; UREA; HEMODIALYSIS; APPETITE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Wang, AYM Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut,Ctr Nutr Studies, Shatin, Hong Kong, Peoples R China Chinese Univ Hong Kong Shatin Hong Kong Peoples R China China
Citazione:
A.Y.M. Wang et al., "Independent effects of residual renal function and dialysis adequacy on actual dietary protein, calorie, and other nutrient intake in patients on continuous ambulatory peritoneal dialysis", J AM S NEPH, 12(11), 2001, pp. 2450-2457

Abstract

Previous studies have suggested that the cross-sectional relationship observed between total solute clearance (Kt/V) and dietary protein intake (DPI)in patients undergoing dialysis is possibly mathematical in origin. A cross-sectional study on 242 patients undergoing continuous ambulatory peritoneal dialysis (CAPD) was performed to determine the differential effects of dialysis adequacy and residual renal function (RRF) on actual dietary intake. All patients underwent a 7-d food frequency questionnaire to quantify daily dietary protein, calorie (DCI), and other nutrient intake, subjective global assessment (SGA), and collection of 24-h dialysate and urine for total(PD and renal) Kt/V and RRF. Patients were categorized into three groups: I (n = 94), total Kt/V greater than or equal to1.7 and GFR >0.5 ml/min per 1.73 m(2); II (n = 58), total Kt/V = greater than or equal to1.7 but GFR <0.5 ml/min per 1.73 m(2); and III (n = 90), total Kt/V <1.7. Sixty-nine percent versus 62% versus 42% of group I versus II versus III patients were well nourished according to SGA (P = 0.004). DPI (1.23 [0.47] versus 1.12 [0.49] versus 0.99 [0.40] g/kg per d; P = 0.002) and DCI (27.3 [8.9] versus 23.8 [8.6] versus 23.0 [8.2] kcal/kg per d; P = 0.002) showed significant decline across the three groups. Intake of other nutrients, including carbohydrate, fat, ratty acids, and cholesterol was higher for group I compared withgroups II and III. Adjusting for age, gender, weight, and diabetes, every 1 ml/min per 1.73 m(2) increase in GFR was associated with a 0.838-fold increase in DCI (95% confidence interval to interval, 0.279 to 1.397, P = 0.003) and a 0.041-fold increase in DPI (95% confidence interval, 0.009 to 0.072; P = 0.012), whereas every 0.25-unit increase in total (PD and renal) Kt/V was associated with a 0.570-fold increase in DCI (95% confidence interval, 0.049 to 1.092; P = 0.032) and a 0.052-fold increase in DPI (95% confidence interval, 0.023 to 0.081; P = 0.001). Greater small-solute clearances are associated with better dietary intake and better nutrition. The study confirmed significant and independent effect of RRF but not PD solute clearance, on actual DPI, DCI, and other nutrient intake in patients on CAPD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:15:37