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Titolo:
Ethanol treatment alters the ultrastructure and permeability of PAN-PVC hollow fiber cell encapsulation membranes
Autore:
Bridge, MJ; Broadhead, KW; Hlady, V; Tresco, PA;
Indirizzi:
Univ Utah, Keck Ctr Tissue Engn, Dept Bioengn, Salt Lake City, UT 84112 USA Univ Utah Salt Lake City UT USA 84112 oengn, Salt Lake City, UT 84112 USA
Titolo Testata:
JOURNAL OF MEMBRANE SCIENCE
fascicolo: 1, volume: 195, anno: 2002,
pagine: 51 - 64
SICI:
0376-7388(20020101)195:1<51:ETATUA>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
PORE-SIZE DISTRIBUTION; PHASE-INVERSION MEMBRANES; ATOMIC-FORCE MICROSCOPY; CENTRAL-NERVOUS-SYSTEM; ULTRAFILTRATION MEMBRANES; TRANSPORT; SOLVENT; MICROSTRUCTURES; TRANSPLANTATION; ORGANS;
Keywords:
atomic force microscopic analysis; ethanol treatment; hollow fiber membrane;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Engineering, Computing & Technology
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Tresco, PA Univ Utah, Keck Ctr Tissue Engn, Dept Bioengn, Room 506,20 South 2030 East, Salt Lake City, UT 84112 USA Univ Utah Room 506,20 South 2030 East Salt Lake City UT USA 84112
Citazione:
M.J. Bridge et al., "Ethanol treatment alters the ultrastructure and permeability of PAN-PVC hollow fiber cell encapsulation membranes", J MEMBR SCI, 195(1), 2002, pp. 51-64

Abstract

Using membrane transport characterization and imaging analysis, we describe a series of studies that indicate that ethanol exposure permanently alters the ultrastructural morphology and the transport properties of FAN-PVC hollow fiber membranes (HFM). In particular, hydropermeability and solute diffusive permeability of ethanol treated sample groups displayed significant increases when compared to that of the untreated controls. Atomic force microscopic analysis revealed significant changes in the morphology of the permselective layer following HFM exposure to ethanol. The results call into question the mechanism by which cell encapsulation HFM confer immune protection when utilized in various transplantation sites in vivo. (C) 2002 Published by Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 12:40:13