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Titolo:
Beneficial effect of alpha-tocopherol in renal ischemia-reperfusion in rats
Autore:
Rhoden, EL; Pereira-Lima, L; Teloken, C; Lucas, ML; Bello-Klein, A; Rhoden, CR;
Indirizzi:
Univ Fed Rio Grande Sul, Porto Alegre Clin Hosp, Postgrad Course Med Clin,BR-90046900 Porto Alegre, RS, Brazil Univ Fed Rio Grande Sul Porto Alegre RS Brazil BR-90046900 BC, RS, Brazil Univ Fed Rio Grande Sul, Santa Casa Hosp, Sch Med Sci, Postgrad Course, BR-90046900 Porto Alegre, RS, Brazil Univ Fed Rio Grande Sul Porto Alegre RSBrazil BR-90046900 BC, RS, Brazil Univ Fed Rio Grande Sul, Santa Casa Hosp, Sch Med Sci, Dept Surg, BR-90046900 Porto Alegre, RS, Brazil Univ Fed Rio Grande Sul Porto Alegre RS Brazil BR-90046900 BC, RS, Brazil Univ Fed Rio Grande Sul, Santa Casa Hosp, Sch Med Sci, Dept Pharmacol, BR-90046900 Porto Alegre, RS, Brazil Univ Fed Rio Grande Sul Porto Alegre RS Brazil BR-90046900 BC, RS, Brazil Univ Fed Rio Grande Sul, Physiol Lab, BR-90046900 Porto Alegre, RS, BrazilUniv Fed Rio Grande Sul Porto Alegre RS Brazil BR-90046900 BC, RS, Brazil
Titolo Testata:
JAPANESE JOURNAL OF PHARMACOLOGY
fascicolo: 2, volume: 87, anno: 2001,
pagine: 164 - 166
SICI:
0021-5198(200110)87:2<164:BEOAIR>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
OXYGEN FREE-RADICALS; INJURY; PREVENTION; DAMAGE;
Keywords:
alpha-tocopherol; renal ischemia-reperfusion; lipid peroxidation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Rhoden, EL Univ Fed Rio Grande Sul, Porto Alegre Clin Hosp, Postgrad Course Med Clin,BR-90046900 Porto Alegre, RS, Brazil Univ Fed Rio Grande Sul Porto Alegre RS Brazil BR-90046900 BCl
Citazione:
E.L. Rhoden et al., "Beneficial effect of alpha-tocopherol in renal ischemia-reperfusion in rats", JPN J PHARM, 87(2), 2001, pp. 164-166

Abstract

We evaluated the effects of alpha -tocopherol (vitamin E) on the products of lipid peroxidation and serum creatinine levels in a rat model of renal ischemia-reperfusion. The animals were submitted to sham operation or renal ischemia-reperfusion, and they were pretreated with alpha -tocopherol or the vehicle saline. In four groups, we analyzed the lipid peroxidation products by measuring malondialdehyde and chemiluminescence levels. In the other three groups, we studied the serum creatinine levels after the procedures. In our study, the pretreatment with alpha -tocopherol reduced significantlythe lipid peroxidation of renal cells and renal dysfunction induced by renal ischemia-reperfusion in rats.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:11:26