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Titolo:
A critical review of akathisia, and its possible association with suicidalbehaviour
Autore:
Hansen, L;
Indirizzi:
Univ Southampton, Mental Hlth Grp, W Local Mental Hlth Team, Southampton SO15 5PQ, Hants, England Univ Southampton Southampton Hants England SO15 5PQ 5 5PQ, Hants, England
Titolo Testata:
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
fascicolo: 7, volume: 16, anno: 2001,
pagine: 495 - 505
SICI:
0885-6222(200110)16:7<495:ACROAA>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLEPTIC-INDUCED AKATHISIA; DRUG-INDUCED AKATHISIA; LOW SERUM IRON; SCHIZOPHRENIC-PATIENTS; TARDIVE-DYSKINESIA; RISK-FACTORS; RAT MODEL; FLUOXETINE; CLOZAPINE; DOPAMINE;
Keywords:
akathisia; suicide; antipsychotics; antidepressants;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
75
Recensione:
Indirizzi per estratti:
Indirizzo: Hansen, L Univ Southampton, Mental Hlth Grp, W Local Mental Hlth Team, Canon House, Southampton SO15 5PQ, Hants, England Univ Southampton Canon HouseSouthampton Hants England SO15 5PQ
Citazione:
L. Hansen, "A critical review of akathisia, and its possible association with suicidalbehaviour", HUM PSYCHOP, 16(7), 2001, pp. 495-505

Abstract

The purpose of this paper was to make a critical review of akathisia, based on the principles of evidence-based medicine, and to explore a possible link between akathisia and suicidal behaviour (suicidal thinking, parasuicide and completed suicide). An extensive systematic search was carried out onthree major databases, Embase, ClinPsych and Medline. Fifty-seven relevantreferences were found, and a further 26 references were reviewed after careful selection from the references of the original references. The CochraneLibrary did not contain any systematic reviews on the subject. Akathisia can be caused by several different groups of drugs, but most frequently by antipsychotics and to a lesser extent antidepressants. Research into akathisia is made considerably more difficult by the lack of a universally agreed definition of the condition. The underlying pathophysiology is still far from clear, but the literature offers guidelines on less hazardous managementregimes for patients. On the basis of the existing literature, akathisia cannot at this stage unequivocally be linked to suicidal behaviour. It is certain, however, that the condition of akathisia does cause considerable distress in an already vulnerable group of patients. Because it is largely avoidable, new, more rigorous strategies must be put in place to prevent it. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/12/19 alle ore 11:44:26