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Titolo:
A novel approach to temporary stenting: degradable cardiovascular stents produced from corrodible metal - results 6-18 months after implantation intoNew Zealand white rabbits
Autore:
Peuster, M; Wohlsein, P; Brugmann, M; Ehlerding, M; Seidler, K; Fink, C; Brauer, H; Fischer, A; Hausdorf, G;
Indirizzi:
Univ Gottingen, Dept Paediat Cardiol & Paediat Intens Care, Childrens Hosp, D-37085 Gottingen, Germany Univ Gottingen Gottingen Germany D-37085 osp, D-37085 Gottingen, Germany Hannover Sch Vet Med, Dept Pathol, D-30559 Hannover, Germany Hannover Sch Vet Med Hannover Germany D-30559 D-30559 Hannover, Germany Univ Essen Gesamthsch, D-45117 Essen, Germany Univ Essen Gesamthsch Essen Germany D-45117 hsch, D-45117 Essen, Germany
Titolo Testata:
HEART
fascicolo: 5, volume: 86, anno: 2001,
pagine: 563 - 569
SICI:
1355-6037(200111)86:5<563:ANATTS>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
TERM FOLLOW-UP; CONGENITAL HEART-DISEASE; BALLOON-EXPANDABLE STENTS; PORCINE CORONARY-ARTERIES; INTRAVASCULAR STENTS; ENDOVASCULAR STENTS; AORTIC COARCTATION; PULMONARY-ARTERY; RECOARCTATION; STENOSIS;
Keywords:
congenital heart disease; corrosion; stents; biodegradation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Peuster, M Univ Gottingen, Dept Paediat Cardiol & Paediat Intens Care, Childrens Hosp, Robert Koch Str 40, D-37085 Gottingen, Germany Univ Gottingen Robert Koch Str 40 Gottingen Germany D-37085 ny
Citazione:
M. Peuster et al., "A novel approach to temporary stenting: degradable cardiovascular stents produced from corrodible metal - results 6-18 months after implantation intoNew Zealand white rabbits", HEART, 86(5), 2001, pp. 563-569

Abstract

Objective-To determine whether corrodible materials may be safely used as biodegradable cardiovascular implants. Design-Corrodible iron stents (> 99.8% iron) were produced from pure iron and laser cut with a stent design similar to a commercially available permanent stent (PUVA-AS16). A total of 16 NOR-I stents were implanted into the native descending aorta of 16 New Zealand white rabbits (mean luminal diameter at the implantation site 3.4 mm, balloon diameter to vessel diameter ratio 1.13). Results-No thromboembolic complications and no adverse events occurred during the follow up of 6-18 months. All stents were patent at repeat angiography after 6 (n = 9), 12 (n = 5), and 18 months (n = 2) with no significant neointimal proliferation, no pronounced inflammatory response, and no systemic toxicity. Conclusions-This initial in vivo experience suggests that degradable iron stents can be safely implanted without significant obstruction of the stented vessel caused by inflammation, neointimal proliferation, or thrombotic events.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 09:28:38