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Titolo:
Washout collaterometry: a new method of assessing collaterals using angiographic contrast clearance during coronary occlusion
Autore:
Seiler, C; Billinger, M; Fleisch, M; Meier, B;
Indirizzi:
Univ Bern, Inselspital, Swiss Cardiovasc Ctr Bern, CH-3010 Bern, Switzerland Univ Bern Bern Switzerland CH-3010 c Ctr Bern, CH-3010 Bern, Switzerland
Titolo Testata:
HEART
fascicolo: 5, volume: 86, anno: 2001,
pagine: 540 - 546
SICI:
1355-6037(200111)86:5<540:WCANMO>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLOW VELOCITY ANALYSIS; ARTERY OCCLUSION; BLOOD-FLOW; ANGIOPLASTY MODEL; HUMANS; PRESSURE; QUANTIFICATION; DETERMINANTS; CIRCULATION; VESSELS;
Keywords:
coronary artery disease; collateral circulation; coronary angiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Seiler, C Univ Bern, Inselspital, Swiss Cardiovasc Ctr Bern, Freiburgstr, CH-3010 Bern, Switzerland Univ Bern Freiburgstr Bern Switzerland CH-3010 ern, Switzerland
Citazione:
C. Seiler et al., "Washout collaterometry: a new method of assessing collaterals using angiographic contrast clearance during coronary occlusion", HEART, 86(5), 2001, pp. 540-546

Abstract

Objective To investigate the hypothesis that the time to washout of radiographic contrast medium trapped distal to an occluded collateral receiving vessel is inversely related to collateral flow, and that this provides an accurate method for characterising coronary collaterals. Methods-An intracoronary pressure derived collateral flow index was determined in 54 patients undergoing percutaneous transluminal coronary balloon angioplasty (PTCA). The study group was subdivided according to whether the collateral vessels were sufficient (n = 17) or insufficient (n = 37) to prevent ECG signs of myocardial ischaemia during PTCA. Washout collaterometry-an angiographic washout method-was carried out simultaneously; after injection of radiographic contrast medium into the collateral receiving vessel followed immediately by vascular occlusion, the number of heart beats was counted until approximately half the length of the epicardial vessel was cleared of contrast. Results-The collateral flow index was higher (0.28 (0.09) v 0.12 (0.07); p< 0.0001) and the contrast washout time shorter (8.0 (2.9) v 17.5 (6.7) heart beats; p < 0.0001) in patients with sufficient versus insufficient collaterals. There was an inverse correlation between contrast washout time andcollateral flow index (r = 0.72, p < 0.0001). Washout of contrast distal to the occluded vessel within I I heart beats correctly determined sufficient and insufficient collaterals with 88% sensitivity and 81% specificity. Conclusions-Washout collaterometry is a new radiographic contrast washout method based on the inverse relation between collateral flow and the time to clearance of radiographic dye injected into the ipsilateral vessel duringPTCA. It appears to be an accurate method of characterising coronary collateral vessels.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:02:12