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Titolo:
Population prevalence, incidence, and predictors of atrial fibrillation inthe Renfrew/Paisley study
Autore:
Stewart, S; Hart, CL; Hole, DJ; McMurray, JJV;
Indirizzi:
Univ Glasgow, Clin Res Initiat Heart Failure, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow Glasgow Lanark Scotland G12 8QQ ow G12 8QQ, Lanark, Scotland Univ Glasgow, Dept Publ Hlth, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow Glasgow Lanark Scotland G12 8QQ ow G12 8QQ, Lanark, Scotland
Titolo Testata:
HEART
fascicolo: 5, volume: 86, anno: 2001,
pagine: 516 - 521
SICI:
1355-6037(200111)86:5<516:PPIAPO>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK-FACTORS; FOLLOW-UP; EPIDEMIOLOGIC FEATURES; HEART-VOLUME; MORTALITY; MEN; WOMEN; PROGNOSIS; SCOTLAND; DISEASE;
Keywords:
atrial fibrillation; epidemiology; systolic blood pressure; cardiac volume;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: McMurray, JJV Univ Glasgow, Clin Res Initiat Heart Failure, Wolfson Bldg Level 3, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow Wolfson Bldg Level 3Glasgow Lanark Scotland G12 8QQ
Citazione:
S. Stewart et al., "Population prevalence, incidence, and predictors of atrial fibrillation inthe Renfrew/Paisley study", HEART, 86(5), 2001, pp. 516-521

Abstract

Objectives-Though atrial fibrillation (AF) is an important cause of cardiovascular morbidity, there are few large epidemiological studies of its prevalence, incidence, and risk factors. The epidemiological features of AF aredescribed in one of the largest population cohorts ever studied. Methods-The prevalence and incidence of AF were studied in the Renfrew/Paisley population cohort of 15 406 men and women aged 45-64 years living in the west of Scotland. This cohort was initially screened between 1972 and 1976 and again between 1977 and 1979. Incident hospitalisations with AF in the 20 year period following initial screening were also studied. Results-The population prevalence of AF in this cohort was 6.5 cases/1000 examinations. Prevalence was higher in men and older subjects. In those whowere rescreened, the four year incidence of AF was 0.54 cases/1000 person years. Radiological cardiomegaly was the most powerful predictor of new AF (adjusted odds ratio 14.0). During 20 year follow up, 3.5% of this cohort was discharged from hospital with a diagnosis of AF; the rate of incident hospitalisation for AF was 1.9 cases/1000 person years. Radiological cardiomegaly (adjusted odds ratio 1.46) and systolic blood pressure (adjusted odds ratio 2.1 for greater than or equal to 169 trim Hg) were independent predictors of this outcome. Conclusions-Data from one of the largest epidemiological studies ever undertaken confirm that AF has a large population prevalence and incidence, even in middle aged people. More important, it was shown that the long term incidence of hospitalisation related to AF is high and that two simple clinical measurements are highly predictive of incident AF. These findings have important implications for the prevention of AF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:34:31