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Titolo:
Dobutamine stress echocardiography versus quantitative technetium-99m sestamibi SPECT for detecting residual stenosis and multivessel disease after myocardial infarction
Autore:
Lancellotti, P; Benoit, T; Rigo, P; Pierard, LA;
Indirizzi:
Univ Hosp Liege, Div Cardiol, B-4000 Liege, Belgium Univ Hosp Liege Liege Belgium B-4000 Div Cardiol, B-4000 Liege, Belgium Univ Hosp Liege, Div Nucl Med, B-4000 Liege, Belgium Univ Hosp Liege Liege Belgium B-4000 Div Nucl Med, B-4000 Liege, Belgium
Titolo Testata:
HEART
fascicolo: 5, volume: 86, anno: 2001,
pagine: 510 - 515
SICI:
1355-6037(200111)86:5<510:DSEVQT>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; SCINTIGRAPHY; SEVERITY; EXTENT; TL-201; ANGIOGRAPHY; MORPHOLOGY; PREDICTION; TOMOGRAPHY; ACCURACY;
Keywords:
myocardial infarction; dobutamine echocardiography; single photon emission computed tomography; SPECT; myocardial ischaemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Pierard, LA Univ Hosp Liege, Div Cardiol, B-4000 Liege, Belgium Univ Hosp Liege Liege Belgium B-4000 , B-4000 Liege, Belgium
Citazione:
P. Lancellotti et al., "Dobutamine stress echocardiography versus quantitative technetium-99m sestamibi SPECT for detecting residual stenosis and multivessel disease after myocardial infarction", HEART, 86(5), 2001, pp. 510-515

Abstract

Objective To compare the relative accuracy of dobutamine stress echo cardiography (DSE) and quantitative technetium-99m sestamibi single photon emission computed tomography (mibi SPECT) for detecting infarct related artery stenosis and multivessel disease early after acute myocardial infarction. Design-Prospective study. Setting-University hospital. Methods-75 patients underwent simultaneous DSE and mibi SPECT at (mean (SD)) 5 (2) days after a first acute myocardial infarct. Quantitative coronaryangiography was performed in all patients after imaging studies. Results-Significant stenosis (> 50%) of the infarct related artery was detected in 69 patients. Residual ischaemia was identified by DSE in 55 patients and by quantitative mibi SPECT in 49. The sensitivity of DSE and mibi SPECT for detecting significant infarct related artery stenosis was 78% and 70%, respectively, with a specificity of 83% for both tests. The combinationof DSE and mibi SPECT did not change the specificity (83%) but increased the sensitivity to 94%. NEW SPECT was more sensitive than DSE for detecting mild stenosis (73% v 9%; p = 0.008). The sensitivity of DSE for detecting moderate or severe stenosis was greater than mibi SPECT (97% v 74%; p = 0.007). Wall motion abnormalities with DSE and transient perfusion defects withmibi SPECT outside the infarction zone were sensitive (80% v 67%; NS) and highly specific (95% v 93%; NS) for multivessel disease. Conclusions-DSE and mibi SPECT have equivalent accuracy for detecting residual infarct related artery stenosis of greater than or equal to 50% and multivessel disease early after acute myocardial infarction. DSE is more predictive of moderate or severe infarct related artery stenosis. Combined imaging only improves the detection of mild stenosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 22:39:44