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Titolo:
Immunohistochemical detection of tyrosine hydroxylase and concentrations of monoamines in the substantia nigra and hypothalamus of hereditary microphthalmic rats
Autore:
Shim, SH; Kim, SJ; Sugahara, K; Sugita, S; Tanaka, H;
Indirizzi:
Utsunomiya Univ, Fac Agr, Dept Appl Biol Chem, Utsunomiya, Tochigi 3218505, Japan Utsunomiya Univ Utsunomiya Tochigi Japan 3218505 , Tochigi 3218505, Japan Utsunomiya Univ, Fac Agr, Dept Anim Sci, Utsunomiya, Tochigi 3218505, Japan Utsunomiya Univ Utsunomiya Tochigi Japan 3218505 , Tochigi 3218505, Japan Chosun Univ, Dept Genet Engn, Kwangju 501759, South Korea Chosun Univ Kwangju South Korea 501759 Engn, Kwangju 501759, South Korea
Titolo Testata:
EXPERIMENTAL ANIMALS
fascicolo: 5, volume: 50, anno: 2001,
pagine: 445 - 449
SICI:
1341-1357(200110)50:5<445:IDOTHA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUPRACHIASMATIC NUCLEUS; DIURNAL FLUCTUATION; CIRCADIAN-RHYTHMS; STRAIN;
Keywords:
catecholamines; microphthalmic rat; tyrosine hydroxylase immunoreactivity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Tanaka, H Utsunomiya Univ, Fac Agr, Dept Appl Biol Chem, 350 Mine, Utsunomiya, Tochigi 3218505, Japan Utsunomiya Univ 350 Mine Utsunomiya Tochigi Japan 3218505 Japan
Citazione:
S.H. Shim et al., "Immunohistochemical detection of tyrosine hydroxylase and concentrations of monoamines in the substantia nigra and hypothalamus of hereditary microphthalmic rats", EXP ANIM, 50(5), 2001, pp. 445-449

Abstract

We compared tyrosine hydroxylase immunoreactivity in the substantia nigra and hypothalamus of hereditary microphthalmic rats with that of normal rats. A considerable number of neuronal cell bodies expressing tyrosine hydroxylase were present in the substantia nigra of the microphthalmic mutant as well as normal rats. Neuronal cells positive for tyrosine hydroxylase in thehypothalamus were fewer than in the substantia nigra in both rats. The concentrations of monoamines (dopamine, noradrenaline, adrenaline, and serotonin) in the substantia nigra and hypothalamus in the microphthalmic mutant were approximately the same as those of normal rats, although the diurnal fluctuation of a few monoamines was observed in normal rats. These results suggest that the metabolic aspects of catecholamine in the substantia nigra and hypothalamus of the microphthalmic mutant rat do not markedly differ from those of normal rats.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 21:41:50