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Titolo:
Risk of bladder cancer by geographic region in a US cohort of male health professionals
Autore:
Michaud, DS; Clinton, SK; Rimm, EB; Willett, WC; Giovannucci, E;
Indirizzi:
Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA Harvard Sch Publ Hlth Boston MA USA Publ Hlth, Dept Nutr, Boston, MA USA Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Harvard Sch Publ Hlth Boston MA USA Hlth, Dept Epidemiol, Boston, MA USA Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Med,Channing Lab, Boston, MA USA Harvard Univ Boston MA USA s Hosp, Dept Med,Channing Lab, Boston, MA USA Ohio State Univ, Arthur G James Canc Hosp, Columbus, OH 43210 USA Ohio State Univ Columbus OH USA 43210 s Canc Hosp, Columbus, OH 43210 USA Ohio State Univ, Richard J Solove Res Inst, Columbus, OH 43210 USA Ohio State Univ Columbus OH USA 43210 ve Res Inst, Columbus, OH 43210 USA
Titolo Testata:
EPIDEMIOLOGY
fascicolo: 6, volume: 12, anno: 2001,
pagine: 719 - 726
SICI:
1044-3983(200111)12:6<719:ROBCBG>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOOD FREQUENCY QUESTIONNAIRE; UNITED-STATES; MORTALITY; SELENIUM; REPRODUCIBILITY; PATTERNS; VALIDITY; MEN;
Keywords:
bladder cancer; geographic variation; cigarette smoking; prospective study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Michaud, DS 6120 Execut Blvd,EPS Rm 7026, Rockville, MD 20852 USA 6120 Execut Blvd,EPS Rm 7026 Rockville MD USA 20852 20852 USA
Citazione:
D.S. Michaud et al., "Risk of bladder cancer by geographic region in a US cohort of male health professionals", EPIDEMIOLOG, 12(6), 2001, pp. 719-726

Abstract

Large regional variations in bladder cancer rates have been observed for numerous decades in the United States and persist to date. We examined the incidence rates of bladder cancer by geographic region among U.S. male health professionals to determine whether diet or other lifestyle factors can account for variations observed. During 12 years of follow-up, 328 cases of bladder cancer were diagnosed in the Health Professionals Follow-up Study Cohort. We inquired about diet, lifetime history of smoking, race, marital status, and other nondietary factors using mailed questionnaires. An elevatedrisk of bladder cancer was observed in the Northeast compared with the West [relative risk (RR) = 1.71, 95% confidence interval (Cl) = 1.23-2.39], which was slightly attenuated after controlling for smoking (RR = 1.65, 95% CI = 1.18-2.30). Smoking patterns, diet, and other lifestyle factors could not account for all of the elevated bladder cancer risk in the Northeast, Bladder cancer risk was highest among men who had a long residency in the Northeast compared with a long residency in the West (RR = 1.77, 95% CI = 1.15-2.71, adjusted for smoking). Diet and other known characteristics do not appear to be responsible for the regional variations in bladder cancer ratesin the United States.

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Documento generato il 28/03/20 alle ore 23:02:03