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Titolo:
Imaging neural activity with temporal and cellular resolution using FISH
Autore:
Guzowski, JF; McNaughton, BL; Barnes, CA; Worley, PF;
Indirizzi:
Univ Arizona, Arizona Res Labs, Div Neural Syst Memory & Aging, Tucson, AZ85724 USA Univ Arizona Tucson AZ USA 85724 Syst Memory & Aging, Tucson, AZ85724 USA Univ Arizona, Dept Psychol, Tucson, AZ 85724 USA Univ Arizona Tucson AZ USA 85724 zona, Dept Psychol, Tucson, AZ 85724 USA Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 urosci, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 Neurol, Baltimore, MD 21205 USA
Titolo Testata:
CURRENT OPINION IN NEUROBIOLOGY
fascicolo: 5, volume: 11, anno: 2001,
pagine: 579 - 584
SICI:
0959-4388(200110)11:5<579:INAWTA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA; HIPPOCAMPAL-NEURONS; PROTEIN EXPRESSION; NERVOUS-SYSTEM; GENE; ARC; TRANSCRIPTS; PATTERNS; INCREASE; FOS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Guzowski, JF Univ Arizona, Arizona Res Labs, Div Neural Syst Memory & Aging, Tucson, AZ85724 USA Univ Arizona Tucson AZ USA 85724 Aging, Tucson, AZ85724 USA
Citazione:
J.F. Guzowski et al., "Imaging neural activity with temporal and cellular resolution using FISH", CUR OP NEUR, 11(5), 2001, pp. 579-584

Abstract

Immediate early genes have gained widespread use as neural activity markers in studies of brain function. The recent development of cellular compartment analysis of temporal activity, which combines sensitive fluorescence insitu hybridization and laser scanning confocal microscopy, overcomes the lack of temporal resolution of standard methodologies and allows the tracking of distinct steps in the synthesis and processing of immediate early geneRNAs. Thus, this technique provides information about when individual neurons are activated and allows the visualization, within a single brain, of different neuronal populations engaged by two distinct experiences.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 15:18:18