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Titolo:
Extracellular matrix composition of full-thickness defect repair tissue islittle influenced by exercise in rat articular cartilage
Autore:
Espanha, MM; Lammi, PE; Hyttinen, MM; Lammi, MJ; Helminen, HJ;
Indirizzi:
Univ Kuopio, Dept Anat, Kuopio 70211, Finland Univ Kuopio Kuopio Finland70211 uopio, Dept Anat, Kuopio 70211, Finland Univ Tecn Lisbon, Fac Human Kinet, P-1495688 Lisbon, Portugal Univ Tecn Lisbon Lisbon Portugal P-1495688 t, P-1495688 Lisbon, Portugal
Titolo Testata:
CONNECTIVE TISSUE RESEARCH
fascicolo: 2, volume: 42, anno: 2001,
pagine: 97 - 109
SICI:
0300-8207(2001)42:2<97:EMCOFD>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTINUOUS PASSIVE MOTION; MODERATE RUNNING EXERCISE; EQUINE CARPUS; CANINE KNEE; II COLLAGEN; CHONDROCYTE TRANSPLANTATION; PHYSICAL EXERCISE; BEAGLE DOGS; X COLLAGEN; RABBIT;
Keywords:
articular cartilage; cartilage repair; proteoglycans; exercise;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Lammi, PE Univ Kuopio, Dept Anat, POB 1627, Kuopio 70211, Finland Univ Kuopio POB 1627 Kuopio Finland 70211 Kuopio 70211, Finland
Citazione:
M.M. Espanha et al., "Extracellular matrix composition of full-thickness defect repair tissue islittle influenced by exercise in rat articular cartilage", CONNECT TIS, 42(2), 2001, pp. 97-109

Abstract

Full-thickness articular cartilage defects in the femoral condyles of adult rats were examined four and eight weeks after injury. Quantitative polarized light microscopic analysis showed that birefringence of the tissue in the central repair area increased more in rats exercised on a treadmill. Glycosaminoglycan content in the repair tissue was also higher than in the intermittent active motion group at four weeks after injury, but by eight weeks the levels were similar in both groups. No normal-looking articular cartilage was formed in the lesions, and only in one animal type II collagen wasobserved in the superficial zone of repair tissue. No 3B3(-) antigenicity of the proteoglycans was seen during repair. In conclusion, exercise minimally modified the repair of full-thickness articular cartilage defects in adult rats. The repair in the exercised group may occur slightly faster in the early stages but no difference was seen at the eight week time interval between the exercised and the intermittently active group.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 18:21:25