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Titolo:
The role of anti-inflammatory drugs in the treatment of osteoarthritis: a European viewpoint
Autore:
Dougados, M;
Indirizzi:
Univ Paris 05, Cochin Hosp, Rheumatol Dept B, F-75014 Paris, France Univ Paris 05 Paris France F-75014 eumatol Dept B, F-75014 Paris, France
Titolo Testata:
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
fascicolo: 6, volume: 19, anno: 2001, supplemento:, 25
pagine: S9 - S14
SICI:
0392-856X(200111/12)19:6<S9:TROADI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PLACEBO-CONTROLLED TRIAL; ARTICULAR-CARTILAGE; STANDING COMMITTEE; OSTEO-ARTHRITIS; II COLLAGEN; KNEE-JOINT; CHONDROCYTES; ACETAMINOPHEN; DEGRADATION;
Keywords:
osteoarthritis; inflammation; arthroscopy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Dougados, M Univ Paris 05, Cochin Hosp, Rheumatol Dept B, 27 Rue Faubourg St Jacques, F-75014 Paris, France Univ Paris 05 27 Rue Faubourg St Jacques Paris France F-75014
Citazione:
M. Dougados, "The role of anti-inflammatory drugs in the treatment of osteoarthritis: a European viewpoint", CLIN EXP RH, 19(6), 2001, pp. S9-S14

Abstract

Despite the fact that there is no scope for an inflammatory process in a strict definition of osteoarthritis (OA), inflammation nevertheless seems tobe of great relevance in understanding not only the occurrence of the disease but also its propensity and/or persistence. Longitudinal epidemiologic studies suggest that inflammation - defined by the presence of synovitis within the joint cavity - is a potent predisposing factor for cartilage breakdown. Nonsteroidal anti-inflammatory drugs (NSAIDs) have demonstrated theirbeneficial short term, rapid-acting effect. However, two questions remain:the choice of NSAIDs versus analysis as first line therapy for symptomatictreatment in OA, and the long-term structural effect of such therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:54:07