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Titolo:
Results of conservative treatment in epithelial ovarian carcinoma
Autore:
Morice, P; Wicart-Poque, F; Rey, A; El-Hassan, J; Pautier, P; Lhomme, C; de Crevoisier, R; Haie-Meder, C; Duvillard, P; Castaigne, D;
Indirizzi:
Inst Gustave Roussy, Serv Chirurg, Dept Surg, F-94805 Villejuif, France Inst Gustave Roussy Villejuif France F-94805 , F-94805 Villejuif, France Inst Gustave Roussy, Dept Biostat, Villejuif, France Inst Gustave Roussy Villejuif France y, Dept Biostat, Villejuif, France Inst Gustave Roussy, Dept Med Oncol, Villejuif, France Inst Gustave Roussy Villejuif France Dept Med Oncol, Villejuif, France Inst Gustave Roussy, Dept Radiotherapy, Villejuif, France Inst Gustave Roussy Villejuif France pt Radiotherapy, Villejuif, France Inst Gustave Roussy, Dept Pathol, Villejuif, France Inst Gustave Roussy Villejuif France sy, Dept Pathol, Villejuif, France
Titolo Testata:
CANCER
fascicolo: 9, volume: 92, anno: 2001,
pagine: 2412 - 2418
SICI:
0008-543X(20011101)92:9<2412:ROCTIE>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
STAGE-I; PROGNOSTIC FACTORS; CANCER; SURGERY; LYMPHADENECTOMY; DYSGERMINOMA; MANAGEMENT; LAPAROTOMY; FERTILITY; PATIENT;
Keywords:
pregnancy; ovarian tumor; conservative surgery; restaging surgery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Morice, P Inst Gustave Roussy, Serv Chirurg, Dept Surg, 39 Rue Camille Desmoulins, F-94805 Villejuif, France Inst Gustave Roussy 39 Rue Camille Desmoulins Villejuif France F-94805
Citazione:
P. Morice et al., "Results of conservative treatment in epithelial ovarian carcinoma", CANCER, 92(9), 2001, pp. 2412-2418

Abstract

BACKGROUND. The objective of this study was to assess and evaluate the clinical outcome and fertility in patients treated conservatively for epithelial ovarian carcinoma (EOC). METHODS. Thirty-one patients treated with conservative management EOC werefollowed up. Optimal surgical staging was performed in 2 cases during the initial surgery and in 27 patients during a reassessment surgery. Six patients underwent hysterectomy during this restaging surgery. RESULTS. Among 25 patients treated conservatively after the restaging surgery, the International Federation of Gynecology and Obstetrics (FIGO) staging distribution was 19 Stage IA (Grade 1, n = 9; Grade 2, n 10), 1 Stage IC, 2 Stage II, and 3 patients with initial stage unknown. Seven patients hadrecurrence (five on the remaining ovary). The disease free survival rate at 5 years for patients with Stage IA Grade I and 2 tumors were 89% and 71%,respectively. All patients with Stage IA or higher disease experienced recurrence. Only four pregnancies (three spontaneous and one after in vitro fertilization procedure) were obtained. CONCLUSIONS. Conservative surgery for patients with EOC could be considered in young patients with Stage IA Grade I disease adequately staged and desiring to preserve fertility potential. This procedure should not performed in patients with disease staged higher than FIGO Stage IA. (C) 2001 American Cancer Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 13:09:44