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Titolo:
Cardiac manifestations of rheumatoid arthritis: A case-control transesophageal echocardiography study in 30 patients
Autore:
Guedes, C; Bianchi-Fior, P; Cormier, B; Barthelemy, B; Rat, AC; Boissier, MC;
Indirizzi:
CHU Bobigny Avicenne AP HP, Serv Rheumatol, F-93009 Bobigny, France CHU Bobigny Avicenne AP HP Bobigny France F-93009 -93009 Bobigny, France Univ Paris 13, Leonardo da Vinci Res Unit, Immunopathol & Immunointervent Res Fdn, Claude Bernard Assoc, Paris, France Univ Paris 13 Paris France Res Fdn, Claude Bernard Assoc, Paris, France Jacques Cartier Hosp, Massy, France Jacques Cartier Hosp Massy FranceJacques Cartier Hosp, Massy, France Univ Paris 13, Bobigny Avicenne Teaching Hosp, Dept Cardiol, Paris, FranceUniv Paris 13 Paris France e Teaching Hosp, Dept Cardiol, Paris, France
Titolo Testata:
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
fascicolo: 2, volume: 45, anno: 2001,
pagine: 129 - 135
SICI:
0004-3591(200104)45:2<129:CMORAA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIOVASCULAR MORTALITY; HEART-DISEASE; INVOLVEMENT; INCOMPETENCE; ABNORMALITIES; PERICARDITIS; REPLACEMENT; PROGNOSIS; FEATURES; SURVIVAL;
Keywords:
rheumatoid arthritis; cardiopathy; echocardiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Boissier, MC CHU Bobigny Avicenne AP HP, Serv Rheumatol, 125 Route Stalingrad, F-93009 Bobigny, France CHU Bobigny Avicenne AP HP 125 Route Stalingrad Bobigny France F-93009
Citazione:
C. Guedes et al., "Cardiac manifestations of rheumatoid arthritis: A case-control transesophageal echocardiography study in 30 patients", ARTH RH ART, 45(2), 2001, pp. 129-135

Abstract

Objectives. Current knowledge of the cardiac manifestations of rheumatoid arthritis (RA) stems only from clinical and transthoracic echocardiography (TTE) studies. To determine the incidence and type of heart lesions in RA, we coupled TTE with transesophageal echocardiography (TEE), which is more sensitive and more accurate. Methods. Thirty unselected RA patients (26 women and 4 men aged 27 to 84 years, with a mean age of 57.8 +/- 15.1 years) free of known progressive heart disease underwent a chest radiograph, an electrocardiogram, laboratory tests, and TTE coupled with TEE. Results were compared with those in age- and sex-matched patients who were free of rheumatic disease and who underwentTEE to investigate a neurologic or cardiologic disorder. Results. Mitral regurgitation (MR) was evidenced in 24 cases (80%). Among the controls, only 11 (37%) had MR (P < 0.001). Aortic regurgitation was found in 10 cases (33%), versus 7 controls (not significant-NS). Seven cases (23%) versus only 2 controls (7%) had tricuspid valve abnormalities (NS). Pericarditis was found in 4 cases (13%) and in none of the controls. Eleven cases had evidence of cardiomyopathy (37%) and 12 (40%) had atheroma of theaorta, this last being missed by TTE in 10 patients. Echo-generating nodules were seen on a mitral valve in 2 cases and on an aortic valve in 1. We found no correlations linking cardiac lesions to clinical or laboratory features of RA. Conclusion. Our study demonstrated that cardiac involvement, particularly of the mitral valve, is extremely common in RA patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 00:54:39