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Titolo:
Visualization of density relations in large-scale neural networks
Autore:
Nadasdy, Z; Zaborszky, L;
Indirizzi:
Rutgers State Univ, Ctr Mol & Behav Neurosci, Newark, NJ 07102 USA RutgersState Univ Newark NJ USA 07102 hav Neurosci, Newark, NJ 07102 USA
Titolo Testata:
ANATOMY AND EMBRYOLOGY
fascicolo: 4, volume: 204, anno: 2001,
pagine: 303 - 317
SICI:
0340-2061(200110)204:4<303:VODRIL>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT BARREL CORTEX; BASAL FOREBRAIN; CHOLINERGIC SYSTEMS; CEREBRAL-CORTEX; ORGANIZATION; PROJECTIONS; NEURONS; CAT; AFFERENTS; STRIATUM;
Keywords:
basal forebrain; cholinergic neurons; calcium-binding protein positive neurons; cell density; voxel; 3D visualization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Zaborszky, L Rutgers State Univ, Ctr Mol & Behav Neurosci, 197 Univ Ave, Newark, NJ 07102 USA Rutgers State Univ 197 Univ Ave Newark NJ USA 07102 07102 USA
Citazione:
Z. Nadasdy e L. Zaborszky, "Visualization of density relations in large-scale neural networks", ANAT EMBRYO, 204(4), 2001, pp. 303-317

Abstract

The topological organization of interfacing neuronal populations in the basal forebrain of rats was investigated in 3D by using computational methodsfor extracting information about the spatial distribution of cell densities and density relations. We claim that numerical and spatial constraints imposed by these methods may help to define neuronal clusters in this brain area where simple two-dimensional histology failed to reveal such an arrangement. Neuronal clusters have been suggested in many brain regions as sites of integrative operations. Taking advantage of computerized data acquisition methods in the 3D reconstruction of large cell populations we introduced four basic methods to visualize density relations on simple and combined cell markers: Differential Density 3D Scatter Plot, Iso-relational Scatter plot, Iso-density Surface Rendering and Iso-relational Surface Rendering. These methods are described and exemplified on a 3D neuronal database acquiredfrom mapping different chemically or hodologically defined cell populations in serial sections of the rat basal forebrain.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 06:45:25