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Titolo:
Quality of life in geriatric depression - A comparison of remitters, partial responders, and nonresponders
Autore:
Doraiswamy, PM; Khan, ZM; Donahue, RMJ; Richard, NE;
Titolo Testata:
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
fascicolo: 4, volume: 9, anno: 2001,
pagine: 423 - 428
SICI:
1064-7481(200123)9:4<423:QOLIGD>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
OF-LIFE; MAJOR DEPRESSION; ELDERLY PATIENTS; SCALE; QLDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Doraiswamy, PM Duke Univ, Med Ctr, Dept Psychiat, Box 3018, Durham, NC 27710 USA Duke Univ Box 3018 Durham NC USA 27710 Durham, NC 27710 USA
Citazione:
P.M. Doraiswamy et al., "Quality of life in geriatric depression - A comparison of remitters, partial responders, and nonresponders", AM J GER PS, 9(4), 2001, pp. 423-428

Abstract

The authors examined patterns of improvement in quality of life (QOL) in elderly patients with recurrent major depression (MDD) after acute treatment. One hundred elderly (age 60-88 years) patients with recurrent MDD were randomized to receive either bupropion sustained-release (100 mg-300 mg/day) or paroxetine (10 mg-40 mg/day) for 6 weeks. Treatment with both paroxetineand bupropion was associated with improvements in QOL, Lower perceived Physical- and Social-Functioning QOL,ratings at baseline were associated with lower treatment response, Improvement in depression symptom ratings correlated significantly with improvement in QOL on many domains but accounted forless than one-quarter of the total variance. Remitters showed significantly (P <0.001) greater improvement than both Partial Responders and Nonresponders on various measures. Findings support the importance of treating elderly depressed patients to full remission to maximize impact on both emotional and physical QOL domains.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 18:39:24