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Titolo:
Diverse BF recombinants have spread widely since the introduction of HIV-1into South America
Autore:
Carr, JK; Avila, M; Carrillo, MG; Salomon, H; Hierholzer, J; Watanaveeradej, V; Pando, MA; Negrete, M; Russell, KL; Sanchez, J; Birx, DL; Andrade, R; Vinoles, J; McCutchan, FE;
Indirizzi:
Henry M Jackson Fdn, Rockville, MD 20850 USA Henry M Jackson Fdn Rockville MD USA 20850 n Fdn, Rockville, MD 20850 USA Natl Reference Ctr AIDS, Buenos Aires, DF, Argentina Natl Reference Ctr AIDS Buenos Aires DF Argentina s Aires, DF, Argentina US Naval Med Res Ctr Detachment, Lima, Peru US Naval Med Res Ctr Detachment Lima Peru es Ctr Detachment, Lima, Peru Walter Reed Army Inst Res, Div Retrovirol, Rockville, MD USA Walter Reed Army Inst Res Rockville MD USA Retrovirol, Rockville, MD USA INLASA, La Paz, Bolivia INLASA La Paz BoliviaINLASA, La Paz, Bolivia Programa Nacl SIDA, Montevideo, Uruguay Programa Nacl SIDA Montevideo Uruguay ma Nacl SIDA, Montevideo, Uruguay
Titolo Testata:
AIDS
fascicolo: 15, volume: 15, anno: 2001,
pagine: F41 - F47
SICI:
0269-9370(20011019)15:15<F41:DBRHSW>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; SUBTYPE-A; TYPE-1; THAILAND;
Keywords:
BF recombinants; circulating recombinant forms; molecular epidemiology; South America;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Carr, JK Henry M Jackson Fdn, 1 Taft Court,Suite 250, Rockville, MD 20850 USA Henry M Jackson Fdn 1 Taft Court,Suite 250 Rockville MD USA 20850
Citazione:
J.K. Carr et al., "Diverse BF recombinants have spread widely since the introduction of HIV-1into South America", AIDS, 15(15), 2001, pp. F41-F47

Abstract

Objective: To describe the genetic diversity of HIV-1 in South America by full genome sequencing and analysis. Methods: Purified peripheral blood mononuclear cell DNA from HIV-infected individuals in Argentina, Uruguay and Bolivia was used to amplify full HIV-1 genomes. These were sequenced using the ABI 3100 automated sequencer and phylogenetically analysed. Results: Twenty-one HIV-1 strains from three South American countries, 17 of which were pre-screened by envelope heteroduplex mobility assay (HMA), were studied. Ten out of 10 HMA subtype F and four out of seven HMA subtype B strains were actually BF recombinants upon full genome analysis. Two BF recombinants from Argentina and two from Uruguay had the same structure, representing a new circulating recombinant form termed CRF12_BFARMA159, Twelveother BF recombinants had structures related to CRF12 but with additional segments of subtype B; each was unique. BF recombinants were temporally andgeographically widespread, found as early as 1986-1987 in vertically infected Argentinian children and in Argentina, Uruguay, and Bolivia. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 18:18:29