Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Efficacy results and quality-of-life measures in men receiving sildenafil citrate for the treatment of erectile dysfunction
Autore:
Giuliano, F; Pena, BM; Mishra, A; Smith, MD;
Indirizzi:
CHU Bicetre, Dept Urol, APHP, Le Kremlin Bicetre, France CHU Bicetre Le Kremlin Bicetre France APHP, Le Kremlin Bicetre, France Pfizer Inc, New York, NY USA Pfizer Inc New York NY USAPfizer Inc, New York, NY USA Pfizer Ltd, Sandwich CT13 9NJ, Kent, England Pfizer Ltd Sandwich Kent England CT13 9NJ andwich CT13 9NJ, Kent, England
Titolo Testata:
QUALITY OF LIFE RESEARCH
fascicolo: 4, volume: 10, anno: 2001,
pagine: 359 - 369
SICI:
0962-9343(2001)10:4<359:ERAQMI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
ORAL SILDENAFIL; ALPROSTADIL THERAPY; CONTROLLED TRIAL; HEALTH SURVEY; DOUBLE-BLIND; IMPOTENCE; SAFETY; PROSTATECTOMY; AGE;
Keywords:
erectile dysfunction; quality of life; sildenafil;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Giuliano, F Hop Bicetre, Dept Urol, 78 Rue Du Gen Leclerc, F-94270 Le Kremlin Bicetre,France Hop Bicetre 78 Rue Du Gen Leclerc Le Kremlin Bicetre France F-94270
Citazione:
F. Giuliano et al., "Efficacy results and quality-of-life measures in men receiving sildenafil citrate for the treatment of erectile dysfunction", QUAL LIFE R, 10(4), 2001, pp. 359-369

Abstract

The aim of the present study was to evaluate the efficacy of sildenafil citrate and its effects on quality of life (QoL) in men with erectile dysfunction (ED) using data from three multicenter, double-blind, placebo-controlled clinical trials. Efficacy was evaluated using a global efficacy question(improvement of erections) and questions from the International Index of Erectile Function (IIEF) addressing the ability to achieve and maintain erections. QoL directly related to ED was evaluated using questions 13 and 14 of the IIEF, several psychometric instruments, and a questionnaire addressing men's concerns about their erection problems. Ninety-seven percent of patients receiving sildenafil reported improved erections compared with 23% ofpatients receiving placebo (p < 0.0001); also reported were improvements in the ability to achieve and maintain erections with sildenafil but not with placebo (p < 0.0001). Improvements were also seen for other aspects of sexual function (overall satisfaction with sex life, sexual relationships with partners, concerns about erectile problems; p < 0.0001) and general mental health (well-being, self-control, satisfaction with relationship, health relative to 1 year ago, mental health; p less than or equal to 0.05) following treatment with sildenafil. Thus, treatment of ED with sildenafil can significantly improve key QoL parameters related to sexual dysfunction and general mental health.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:38:44