Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Transcranial magnetic stimulation for depression and other psychiatric disorders
Autore:
McNamara, B; Ray, JL; Arthurs, OJ; Boniface, S;
Indirizzi:
Addenbrookes Hosp, Dept Clin Neurophysiol, Cambridge Transcranial Magnet Stimulat Grp, Cambridge CB2 2QQ, England Addenbrookes Hosp Cambridge England CB2 2QQ , Cambridge CB2 2QQ, England
Titolo Testata:
PSYCHOLOGICAL MEDICINE
fascicolo: 7, volume: 31, anno: 2001,
pagine: 1141 - 1146
SICI:
0033-2917(200110)31:7<1141:TMSFDA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEXAMETHASONE SUPPRESSION TEST; PREFRONTAL CORTEX; MAJOR DEPRESSION; ELECTROCONVULSIVE-THERAPY; RESISTANT DEPRESSION; SLOW; RTMS; MOOD; TRIAL; RAT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Boniface, S Addenbrookes Hosp, Dept Clin Neurophysiol, Cambridge Transcranial Magnet Stimulat Grp, Box 124,Hills Rd, Cambridge CB2 2QQ, England Addenbrookes Hosp Box 124,Hills Rd Cambridge England CB2 2QQ
Citazione:
B. McNamara et al., "Transcranial magnetic stimulation for depression and other psychiatric disorders", PSYCHOL MED, 31(7), 2001, pp. 1141-1146

Abstract

Introduction. Repetitive transcranial magnetic stimulation (rTMS) has beenproposed as a possible alternative to electroconvulsive therapy for the treatment of selected patients with depression, bipolar affective disorder and schizophrenia. The aim of this study was to evaluate the evidence for theeffectiveness of rTMS in mood disorders and schizophrenia. Methods. Studies were identified using MEDLINE (1966 to January 2000), EMBASE/Excerpta Medica (1980 to January 2000), Biological Abstracts and Index to Scientific and Technical Proceedings. A number of biomedical and TMS related websites were also searched. We estimated the number needed to treat to show beneficial effect of rTMS when compared with the placebo controlled group. Results. Seven controlled trials of rTMS depression were identified. Five of these were suitable for meta-analysis and show a beneficial effect of rTMS compared to placebo, with a number needed to treat of 2(.)3 with a 95% confidence interval 1(.)6 to 4(.)0, total; 81 patients. A single trial of rTMS has also been performed in mania, which shows a beneficial effect of right hemisphere stimulation when compared with left hemisphere stimulation. Acontrolled trial in schizophrenia failed to show any benefit of rTMS. Discussion. rTMS has demonstrable beneficial effects in depression. The extent and the duration of the anti-depressant effect of rTMS has yet to be defined. There now needs to be randomized controlled trials to compare rTMS directly with standardized electroconvulsive therapy in order to take this subject forward. With regard to the treatment of other mood disorders and schizophrenia, we are at an early stage in the assessment of further studiesthat are needed to examine any potential role for rTMS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 08:56:14