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Titolo:
Microstructured glass chip for ion-channel electrophysiology - art. no. 040901
Autore:
Fertig, N; Meyer, C; Blick, RH; Trautmann, C; Behrends, JC;
Indirizzi:
Univ Munich, Ctr Nanosci, D-80539 Munich, Germany Univ Munich Munich Germany D-80539 Ctr Nanosci, D-80539 Munich, Germany Univ Munich, Sekt Phys, D-80539 Munich, Germany Univ Munich Munich Germany D-80539 h, Sekt Phys, D-80539 Munich, Germany Univ Munich, Inst Physiol, D-80336 Munich, Germany Univ Munich Munich Germany D-80336 Inst Physiol, D-80336 Munich, Germany Gesell Schwerionenforsch mbH, D-64291 Darmstadt, Germany Gesell Schwerionenforsch mbH Darmstadt Germany D-64291 armstadt, Germany
Titolo Testata:
PHYSICAL REVIEW E
fascicolo: 4, volume: 6404, anno: 2001,
parte:, 1
pagine: 0901 -
SICI:
1063-651X(200110)6404:4<0901:MGCFIE>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATCH-CLAMP TECHNIQUES; HIGH-RESOLUTION; MEMBRANE PATCHES; MONOLAYERS; RECORDINGS; GRAMICIDIN; NOISE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
--discip_EC--
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Fertig, N Univ Munich, Ctr Nanosci, Geschwister Scholl Pl 1, D-80539 Munich, Germany Univ Munich Geschwister Scholl Pl 1 Munich Germany D-80539 many
Citazione:
N. Fertig et al., "Microstructured glass chip for ion-channel electrophysiology - art. no. 040901", PHYS REV E, 6404(4), 2001, pp. 0901

Abstract

We present a technique by which it is possible to produce a planar sensor for ion channel electrophysiology from glass substrates. Apertures with diameters in the low micrometer to submicrometer range are achieved by irradiation of a glass chip with a single heavy ion and subsequent wet track etching. The function of the device is demonstrated by recordings of single channel currents mediated by the model ion channel gramicidin A in lipid bilayers, spanning the micromachined aperture.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:34:15