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Titolo:
Use of rapacuronium in a child with spinal muscular atrophy
Autore:
Stucke, AG; Stuth, EAE;
Indirizzi:
Vet Adm Med Ctr, Anesthesia Res Serv 151, Milwaukee, WI 53295 USA Vet Adm Med Ctr Milwaukee WI USA 53295 Serv 151, Milwaukee, WI 53295 USA Childrens Hosp Wisconsin, Sect Pediat Anesthesia, Milwaukee, WI 53201 USA Childrens Hosp Wisconsin Milwaukee WI USA 53201 , Milwaukee, WI 53201 USA
Titolo Testata:
PAEDIATRIC ANAESTHESIA
fascicolo: 6, volume: 11, anno: 2001,
pagine: 725 - 728
SICI:
1155-5645(200111)11:6<725:UORIAC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
MUSCLE-RELAXANTS; ANESTHESIA;
Keywords:
lower motor neurone disease; rapacuronium; nondepolarizing muscle relaxant; succinylcholine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Stucke, AG Vet Adm Med Ctr, Anesthesia Res Serv 151, 5000 W Natl Ave, Milwaukee, WI 53295 USA Vet Adm Med Ctr 5000 W Natl Ave Milwaukee WI USA 53295 3295 USA
Citazione:
A.G. Stucke e E.A.E. Stuth, "Use of rapacuronium in a child with spinal muscular atrophy", PAEDIATR AN, 11(6), 2001, pp. 725-728

Abstract

We report the case of an 18-month-old girl with spinal muscular atrophy (SMA) that received 1 mg.kg(-1) rapacuronium for laryngospasm during induction of anaesthesia. Within 15 min, we observed some diaphragmatic recovery and, after emergence from anaesthesia, the child demonstrated adequate respiratory efforts. However, the child showed diminished strength of the upper extremity muscles. Since the preoperative workup had revealed bulbar symptoms and laryngeal function could not be easily assessed, the patient was keptintubated until upper extremity strength had returned to preoperative levels. Small doses of midazolam had been given to reduce the patient's anxietybut the patient was extubated within 5 h without any complications. Train of four (TOF) monitoring of the right adductor pollicis muscle, performed during anaesthetic recovery, was equivocal. In SMA, muscle groups are differentially affected so that TOF responses may be inconclusive and not reflectthe state of the upper airway muscles. To our knowledge, this is the firstreport of use of a nondepolarizing neuromuscular blocking agent in a childwith SMA.

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Documento generato il 29/11/20 alle ore 02:16:40