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Titolo:
Stem cell factor regulation of Fas-mediated apoptosis of human erythroid precursor cells
Autore:
Oda, A; Nishio, M; Sawada, K;
Indirizzi:
Hokkaido Univ, Sch Med, Dept Internal Med 2, Kita Ku, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608638 oro, Hokkaido 0608638, Japan Hokkaido Univ, Sch Med, Lab Environm Biol, Dept Prevent Med, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608638 oro, Hokkaido 0608638, Japan
Titolo Testata:
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
fascicolo: 5, volume: 10, anno: 2001,
pagine: 595 - 600
SICI:
1525-8165(200110)10:5<595:SCFROF>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMATOPOIETIC PROGENITOR CELLS; NECROSIS-FACTOR-ALPHA; COLONY-FORMING CELLS; GROWTH-FACTOR-I; C-KIT LIGAND; INTERFERON-GAMMA; MYELODYSPLASTIC SYNDROMES; BONE-MARROW; FUNCTIONAL EXPRESSION; SIGNAL-TRANSDUCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Sawada, K Hokkaido Univ, Sch Med, Dept Internal Med 2, Kita Ku, N-15,W-7, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ N-15,W-7 Sapporo Hokkaido Japan 0608638 638, Japan
Citazione:
A. Oda et al., "Stem cell factor regulation of Fas-mediated apoptosis of human erythroid precursor cells", J HEMATH ST, 10(5), 2001, pp. 595-600

Abstract

Multiple cytokines regulate the development of erythrocytes. Increasing attention has been directed to the possible role of Fas and its cognate ligand (Fas-L), a subject of wide interest. Documentation of in vitro data supports the role of Fas and Fas-L in erythropoiesis. Several laboratories, including ours, investigated the opposing actions of erythropoietin (EPO) and stem cell factor (SCF) on Fas-mediated cell death of the erythroid cells. Only circumstantial in vivo evidence has accumulated concerning the issue. There are several reports suggesting that Fas-mediated cell death may have a role in some pathological conditions. Results of the accumulating findings and possible implications in clinical hematology are summarized in this review.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 06:32:49