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Titolo:
Evaluation of the use of evidence-based angiotensin-converting enzyme inhibitor criteria for the treatment of congestive heart failure: opportunitiesfor pharmacists to improve patient outcomes
Autore:
Pearson, GJ; Cooke, C; Simmons, WKT; Sketris, I;
Indirizzi:
Univ Alberta, Fac Med & Dent, Div Cardiol, Heritage Med Res Ctr 213, Edmonton, AB T6G 2S2, Canada Univ Alberta Edmonton AB Canada T6G 2S2 213, Edmonton, AB T6G 2S2, Canada Dalhousie Univ, Fac Med, Dept Epidemiol & Community Hlth, Halifax, NS, Canada Dalhousie Univ Halifax NS Canada l & Community Hlth, Halifax, NS, Canada Queen Elizabeth II Hlth Sci Ctr, Dept Pharm, Halifax, NS, Canada Queen Elizabeth II Hlth Sci Ctr Halifax NS Canada m, Halifax, NS, Canada Queen Elizabeth II Hlth Sci Ctr, Div Hematol, Halifax, NS, Canada Queen Elizabeth II Hlth Sci Ctr Halifax NS Canada l, Halifax, NS, Canada Dalhousie Univ, Coll Pharm, Halifax, NS B3H 3J5, Canada Dalhousie Univ Halifax NS Canada B3H 3J5 arm, Halifax, NS B3H 3J5, Canada
Titolo Testata:
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
fascicolo: 5, volume: 26, anno: 2001,
pagine: 351 - 361
SICI:
0269-4727(200110)26:5<351:EOTUOE>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR SYSTOLIC DYSFUNCTION; ELDERLY PATIENTS; MULTIDISCIPLINARY INTERVENTION; MYOCARDIAL-INFARCTION; PRACTICE GUIDELINES; DRUG UTILIZATION; ACE-INHIBITORS; RENAL-FUNCTION; MANAGEMENT; MORTALITY;
Keywords:
angiotensin-converting enzyme inhibitors; congestive heart failure; drug utilization evaluation (DUE); drug utilization review (DUR); guidelines;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Pearson, GJ Univ Alberta, Fac Med & Dent, Div Cardiol, Heritage Med Res Ctr 213, Edmonton, AB T6G 2S2, Canada Univ Alberta Edmonton AB Canada T6G 2S2 n, AB T6G 2S2, Canada
Citazione:
G.J. Pearson et al., "Evaluation of the use of evidence-based angiotensin-converting enzyme inhibitor criteria for the treatment of congestive heart failure: opportunitiesfor pharmacists to improve patient outcomes", J CLIN PH T, 26(5), 2001, pp. 351-361

Abstract

Background: The under-utilization and underdosing of angiotensin-converting enzyme inhibitors (ACEIs) in patients with congestive heart failure (CHF)continues to be a problem observed in clinical practice. Objective: To develop and implement drug use evaluation (DUE) criteria forthe use of ACEIs in patients with CHF which could be used by pharmacists to ensure that all eligible patients receive an ACEI at an appropriate dose. Methods: A retrospective chart review of all patients discharged from the study institution with a diagnosis of CHF during the period of March 1 to July 31, 1998 was conducted using the DUE criteria developed. Results: Of the 138 patients evaluated, only 68.6% were discharged on ACEItherapy. Additionally, only 40% of those discharged on an ACEI achieved target dose. Multiple regression analysis revealed that males were 2.43 timesmore likely to be discharged on an ACEI than females, while those on concomitant diuretics or digoxin were less likely to be discharged on an ACEI (25% and 18%, respectively). Conclusions: The application of these DUE criteria by pharmacists in hospital and community practice has the potential to improve utilization and dosing of this important class of medications for the management of the symptoms and progression of CHF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/08/20 alle ore 18:16:46