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Titolo:
Acute motor-sensory axonal neuropathy associated with active systemic lupus erythematosus and anticardiolipin antibodies
Autore:
Ubogu, EE; Zaidat, OO; Suarez, JI;
Indirizzi:
Case Western Reserve Univ, Univ Hosp Cleveland, Sch Med, Dept Neurol, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Case Western Reserve Univ, Univ Hosp Cleveland, Sch Med, Dept Neurol Surg,Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 ,Cleveland, OH 44106 USA
Titolo Testata:
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
fascicolo: 5, volume: 7, anno: 2001,
pagine: 326 - 331
SICI:
1076-1608(200110)7:5<326:AMANAW>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
GUILLAIN-BARRE-SYNDROME; NORTHERN CHINA; INTRAVENOUS IMMUNOGLOBULIN; PERIPHERAL NEUROPATHY; DISEASE; SPECTRUM; DEGENERATION; GLOBULIN;
Keywords:
anticardiolipin antibodies; axonal neuropathy; Guillian-Barre syndrome; polyradiculoneuropathy; systemic lupus erythematosus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Ubogu, EE Case Western Reserve Univ, Univ Hosp Cleveland, Sch Med, Dept Neurol, Hanna House,5th Floor,11000 Euclid Ave, Cleveland, OH 44106 USA Case Western Reserve Univ Hanna House,5th Floor,11000 Euclid Ave Cleveland OH USA 44106
Citazione:
E.E. Ubogu et al., "Acute motor-sensory axonal neuropathy associated with active systemic lupus erythematosus and anticardiolipin antibodies", JCR-J CLIN, 7(5), 2001, pp. 326-331

Abstract

Acute motor-sensory axonal neuropathy (AMSAN) is an axonal variant of Guillian-Barre syndrome (GBS) that presents with acute ascending quadriparesis. This has generally been described in association with Campylobacter jejuniinfections or with antiganglioside antibodies. Known cases have shown a slow recovery and a poor prognosis. We report a case with clinical and electrophysiological evidence of AMSAN in association with active systemic lupus erythematosus (SLE) and anticardiolipin antibodies but not the other associations, with a rapid response to combination immunosuppressant and intravenous immunoglobulin (Mg) therapy. The association between AMSAN and SLE has not been previously described. This case illustrates that early recognitionand the utilization of electrophysiologic techniques may be beneficial in the diagnosis and management of GBS associated with SLE. Fulminant or rapidly progressive cases should be managed in specialized intensive care units. Combination therapy of immunosuppressants, and IVIg may be beneficial in nonvasculitic axonal radiculoneuropathies associated with SLE, resulting in good outcomes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:39:50