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Titolo:
Resistance of T-cell receptor 8-chain-deficient mice to experimental Candida albicans vaginitis
Autore:
Wormley, FL; Steele, C; Wozniak, K; Fujihashi, K; McGhee, JR; Fidel, PL;
Indirizzi:
Louisiana State Univ, Hlth Sci Ctr, Dept Microbiol Immunol & Parasitol, New Orleans, LA 70112 USA Louisiana State Univ New Orleans LA USA 70112 , New Orleans, LA 70112 USA Univ Alabama, Med Ctr, Immunobiol Vaccine Ctr, Birmingham, AL 35294 USA Univ Alabama Birmingham AL USA 35294 accine Ctr, Birmingham, AL 35294 USA
Titolo Testata:
INFECTION AND IMMUNITY
fascicolo: 11, volume: 69, anno: 2001,
pagine: 7162 - 7164
SICI:
0019-9567(200111)69:11<7162:ROTR8M>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL VAGINAL CANDIDIASIS; MEDIATED-IMMUNITY; ALPHA-BETA; PHENOTYPICALLY DISTINCT; INFECTION; RESPONSES; DEFICIENT; SUBSET;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Fidel, PL Louisiana State Univ, Hlth Sci Ctr, Dept Microbiol Immunol & Parasitol, 1901 Perdido St, New Orleans, LA 70112 USA Louisiana State Univ 1901 Perdido St New Orleans LA USA 70112 SA
Citazione:
F.L. Wormley et al., "Resistance of T-cell receptor 8-chain-deficient mice to experimental Candida albicans vaginitis", INFEC IMMUN, 69(11), 2001, pp. 7162-7164

Abstract

Conditions consistent with tolerance or immunoregulation have been observed in experimental Candida albicans vaginal infections. The present study investigated the role of gamma/delta T cells in experimental vaginal candidiasis. Results showed that T-cell receptor delta -chain-knockout mice had significantly less vaginal fungal burden when compared to wild-type mice, suggesting an immunoregulatoty role for gamma/delta T cells in Candida vaginitis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 03:48:39