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Titolo:
Conceptual design of a compact positron tomograph for prostate imaging
Autore:
Huber, JS; Derenzo, SE; Qi, J; Moses, WW; Huesman, RH; Budinger, TF;
Indirizzi:
Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA Lawrence Berkeley Natl Lab Berkeley CA USA 94720 , Berkeley, CA 94720 USA
Titolo Testata:
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
fascicolo: 4, volume: 48, anno: 2001,
parte:, 2
pagine: 1506 - 1511
SICI:
0018-9499(200108)48:4<1506:CDOACP>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-11 CHOLINE PET; CLINICAL-TRIALS; RESOLUTION; RECONSTRUCTION; CANCER; PERFORMANCE; ANTIGEN; SCANNER; TUMOR;
Keywords:
biomedical imaging; positron emission tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Engineering, Computing & Technology
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Huber, JS Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA Lawrence Berkeley Natl Lab Berkeley CA USA 94720 , CA 94720 USA
Citazione:
J.S. Huber et al., "Conceptual design of a compact positron tomograph for prostate imaging", IEEE NUCL S, 48(4), 2001, pp. 1506-1511

Abstract

We present a conceptual design of a compact positron tomograph for prostate imaging using a pair of external curved detector banks, one placed above and one below the patient. The lower detector bank is fixed below the patient bed, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 conventional block detectors, forming two arcs (44 cm minor, 60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point toward the prostate to minimize resolution degradation in that region. Interplane septa extend 5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility of detecting and differentiating partial and whole prostate tumors with a tumor-to-background ratio of 2:1, utilizing the number of events that should be achievable with a 6-min scan after a 10 mCi injection (e.g., carbon-11 choline or fluorine-18 fluorocholine).

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Documento generato il 27/11/20 alle ore 02:20:54