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Titolo:
Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes
Autore:
Tenney, CR; Tornai, MP; Smith, MF; Turkington, TG; Jaszczak, RJ;
Indirizzi:
Duke Univ, Med Ctr, Durham, NC 27710 USA Duke Univ Durham NC USA 27710Duke Univ, Med Ctr, Durham, NC 27710 USA NIH, Bethesda, MD 20892 USA NIH Bethesda MD USA 20892NIH, Bethesda, MD 20892 USA
Titolo Testata:
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
fascicolo: 4, volume: 48, anno: 2001,
parte:, 2
pagine: 1483 - 1489
SICI:
0018-9499(200108)48:4<1483:UPCF5P>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ULTRA-HIGH-RESOLUTION; EMISSION COMPUTED-TOMOGRAPHY; PET SCANNER; SMALL ANIMALS; PERFORMANCE; DESIGN; SYSTEM; PENETRATION; SENSITIVITY; MICROPET;
Keywords:
depleted uranium; pinhole collimator; small animal biomedical imaging; single photon emission computed tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Engineering, Computing & Technology
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Tenney, CR Thomas Jefferson Univ, Philadelphia, PA 19107 USA Thomas Jefferson Univ Philadelphia PA USA 19107 , PA 19107 USA
Citazione:
C.R. Tenney et al., "Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes", IEEE NUCL S, 48(4), 2001, pp. 1483-1489

Abstract

Depleted uranium (DU) pinhole collimators are evaluated for small-volume SPECT imaging of 511-keV gammas, with a view toward small-animal imaging. Tungsten (W) pinholes are examined for comparison. Line source measurements show planar full-width at half-maximum (FWHM) as low as 6.5 mm for a 1-mm DUpinhole, with SPECT system FWHM of 5.0 mm at 43-mm ROR and 6.7 mm at 69-mmROR. Planar FWHM is smaller for DU than for W pinholes but is insensitive to aperture size for pinholes of 1-3 rum diameter at this energy for the collimators studied. These trends indicate penetration at pinhole edges, as confirmed by LSF shape and full-width at tenth-maximum trends. In SPECT scans of rod phantoms at 71-mm ROR, DU pinholes were only barely able to resolve cold rods as large as 4.7 mm (center-to-center spacing = 2 x diameter). For both F-18 alone and F-18 imaged along with Tc-99m, 3.9-mm hot rods were resolved. Te-99m scans resolved 2.3-mm rods with F-18 present and 1.5-mm rods without F-18. DU pinhole SPECT at 511 keV does not currently match the spatial resolution of high-resolution positron emission tomography (PET) butis open to improvement and, unlike PET, is capable of simultaneous multiple-isotope acquisitions.

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Documento generato il 18/01/20 alle ore 01:56:07