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Titolo:
Large B-cell lymphoma of the leg - Complete remission with perilesional interferon alpha
Autore:
Wollina, U; Mentzel, T; Graefe, T;
Indirizzi:
Univ Jena, Dept Dermatol & Allergol, D-07740 Jena, Germany Univ Jena Jena Germany D-07740 ermatol & Allergol, D-07740 Jena, Germany Dermatohistopathol Lab Hugel Kutzner Rutten Mentz, Friedrichshafen, Germany Dermatohistopathol Lab Hugel Kutzner Rutten Mentz Friedrichshafen Germany
Titolo Testata:
DERMATOLOGY
fascicolo: 2, volume: 203, anno: 2001,
pagine: 165 - 167
SICI:
1018-8665(2001)203:2<165:LBLOTL>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY CUTANEOUS LYMPHOMAS; THERAPY; RITUXIMAB; SKIN;
Keywords:
large B-cell lymphoma of the leg; interferon alpha; matrix metalloproteinase 2; soluble intercellular adhesion molecule 1;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Wollina, U Univ Jena, Dept Dermatol & Allergol, ERfurter Str 35, D-07740 Jena, Germany Univ Jena ERfurter Str 35 Jena Germany D-07740 0 Jena, Germany
Citazione:
U. Wollina et al., "Large B-cell lymphoma of the leg - Complete remission with perilesional interferon alpha", DERMATOLOGY, 203(2), 2001, pp. 165-167

Abstract

We present the case of an 85-year-old woman with cutaneous and subcutaneous nodules on the lower and upper leg showing the characteristic histological features of a large B-cell lymphoma of the leg. Investigations for non-Hodgkin's lymphoma with the prognostic markers matrix metalloproteinase 2 andsoluble intercellular adhesion molecule 1 revealed an increased serum level of the latter. Monotherapy with perilesional interferon alpha (2a) 3 x 9 million units/week was well tolerated. The final outcome was a complete remission after 14 months with an overall survival of more than 17 months. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:23:26