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Titolo:
Does a single vitamin B-supplementation induce functional vitamin B-deficiency?
Autore:
Naurath, HJ; Riezler, R; Putter, S; Ubbink, JB;
Indirizzi:
Friedrich Ebert Hosp, Geriatr Klin, D-24534 Neumunster, Germany Friedrich Ebert Hosp Neumunster Germany D-24534 4534 Neumunster, Germany Severi Med, Munster, Germany Severi Med Munster GermanySeveri Med, Munster, Germany Medice, Iserlohn, Germany Medice Iserlohn GermanyMedice, Iserlohn, Germany Univ Pretoria, Dept Chem Pathol, ZA-0002 Pretoria, South Africa Univ Pretoria Pretoria South Africa ZA-0002 -0002 Pretoria, South Africa
Titolo Testata:
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
fascicolo: 8, volume: 39, anno: 2001,
pagine: 768 - 771
SICI:
1434-6621(200108)39:8<768:DASVBI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHROMATOGRAPHY MASS-SPECTROMETRY; PLASMA HOMOCYSTEINE; VASCULAR-DISEASE; ELDERLY PEOPLE; NORMAL SERUM; RISK FACTOR; FOLIC-ACID; HYPERHOMOCYSTEINEMIA; METHIONINE; METABOLISM;
Keywords:
homocysteine; methylmalonic acid; cystathionine; vitamin B-6; vitamin B-12; folate; vitamin B depletion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Naurath, HJ Friedrich Ebert Hosp, Geriatr Klin, Friesenstr 11, D-24534 Neumunster, Germany Friedrich Ebert Hosp Friesenstr 11 Neumunster Germany D-24534
Citazione:
H.J. Naurath et al., "Does a single vitamin B-supplementation induce functional vitamin B-deficiency?", CLIN CH L M, 39(8), 2001, pp. 768-771

Abstract

In a pilot study we measured the effect of three different combinations ofthe vitamins B-6, folate and B-12 on the serum concentrations of homocysteine, cystathionine and methylmalonic acid in five healthy young men withouthyperhomocysteinemia. The results indicate that there are still undescribed interactions between vitamin B-6 and follate, suggesting that these two vitamins should be given together to avoid depletion of the one not given. With regard to the well known metabolic pathways of methionine and cysteine,this confirms the hypothesis that a combined supplementation with the vitamins B-6 and folate (and B-12) is superior to folate alone in order to lower homocysteine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 00:19:53