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Titolo:
Immunocytochemistry in effusion cytology - A contemporary review
Autore:
Fetsch, PA; Abati, A;
Indirizzi:
NCI, Cytopathol Sect, NIH, Bethesda, MD 20892 USA NCI Bethesda MD USA 20892 I, Cytopathol Sect, NIH, Bethesda, MD 20892 USA
Titolo Testata:
CANCER CYTOPATHOLOGY
fascicolo: 5, volume: 93, anno: 2001,
pagine: 293 - 308
SICI:
0008-543X(20011025)93:5<293:IIEC-A>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIFFERENTIATING EPITHELIAL MESOTHELIOMA; LOGISTIC-REGRESSION ANALYSIS; MALIGNANT MESOTHELIOMA; E-CADHERIN; SEROUS EFFUSIONS; N-CADHERIN; IMMUNOHISTOCHEMICAL DIAGNOSIS; METASTATIC ADENOCARCINOMA; PLEURAL MESOTHELIOMAS; LUNG ADENOCARCINOMAS;
Keywords:
immunocytochemistry; effusion; adenocarcinoma (ACA); malignant mesothelioma (MM); cytospin; cell block; ThinPrep;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
81
Recensione:
Indirizzi per estratti:
Indirizzo: Abati, A NCI, Cytopathol Sect, NIH, Bldg 10,Room 2A19, Bethesda, MD 20892 USA NCI Bldg 10,Room 2A19 Bethesda MD USA 20892 ethesda, MD 20892 USA
Citazione:
P.A. Fetsch e A. Abati, "Immunocytochemistry in effusion cytology - A contemporary review", CANC CYTOP, 93(5), 2001, pp. 293-308

Abstract

BACKGROUND. Cytology plays a pivotal role in the diagnosis of pleural effusions. In many cases, immunocytochemistry (ICC) is required to elucidate the etiology of the atypical cells. Effusions are samples that present uniqueproblems for ICC. To date there is no standardization of ICC methods for effusions and cytology in general. METHODS. The authors review the most commonly used cytologic preparations,fixatives, and antibodies used in effusion ICC. RESULTS. Through the utilization of cell block preparations and a panel ofantibodies appropriate for the differential diagnosis in question, ICC conditions utilized in surgical pathology can be most closely replicated. CONCLUSIONS. ICC may provide reliable insights into various diagnostic dilemmas in effusion cytology, provided that laboratory standardization practices are followed. (C) 2001 American Cancer Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:07:37