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Titolo:
Basolateral amygdala lesions disrupt latent inhibition in rats
Autore:
Coutureau, E; Blundell, PJ; Killcross, S;
Indirizzi:
Cardiff Univ, Sch Psychol, Cardiff CF10 3YG, S Glam, Wales Cardiff Univ Cardiff S Glam Wales CF10 3YG ardiff CF10 3YG, S Glam, Wales Univ York, Dept Psychol, York YO1 5DD, N Yorkshire, England Univ York York N Yorkshire England YO1 5DD YO1 5DD, N Yorkshire, England
Titolo Testata:
BRAIN RESEARCH BULLETIN
fascicolo: 1, volume: 56, anno: 2001,
pagine: 49 - 53
SICI:
0361-9230(20010901)56:1<49:BALDLI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENTORHINAL CORTEX; RETROHIPPOCAMPAL REGION; HIPPOCAMPUS; BRAIN; REINFORCEMENT; HALOPERIDOL; SPECIFICITY; AMPHETAMINE; PROJECTIONS; COMPLEX;
Keywords:
latent inhibition; basolateral amygdala; appetitive conditioning; schizophrenia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Coutureau, E Cardiff Univ, Sch Psychol, POB 901,Tower Bldg,Pk Pl, Cardiff CF10 3YG, S Glam, Wales Cardiff Univ POB 901,Tower Bldg,Pk Pl Cardiff S Glam Wales CF10 3YG
Citazione:
E. Coutureau et al., "Basolateral amygdala lesions disrupt latent inhibition in rats", BRAIN RES B, 56(1), 2001, pp. 49-53

Abstract

Latent inhibition (LI) refers to the retardation of acquisition of conditioned responding produced by repeated non-reinforced preexposure to the conditioned stimulus (CS) prior to its pairing with the unconditioned stimulus (US) during conditioning. Ll has recently been shown to depend upon the integrity of temporal lobe structures, including regions of the hippocampal formation such as the entorhinal cortex. The present study investigated the effects of excitotoxic lesions of another temporal lobe structure, the basolateral nucleus of the amygdala (BLA), on Ll. Ll was studied in a within-subjects appetitive conditioning preparation in which an auditory CS was paired with food US. In this procedure, preexposure to the CS results in slower acquisition of magazine approach behaviour. Lesions of the BLA reduced the effect of preexposure, disrupting Ll. This result suggests that the BLA canplay a crucial role in Ll. The possible involvement of interactions between BLA and entorhinal cortex in LI is discussed. (C) 2001 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 22:14:26