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Titolo:
Evidence-based management of osteoarthritis: practical issues relating to the data
Autore:
Doherty, M; Dougados, M;
Indirizzi:
City Hosp, Nottingham NG5 1PB, England City Hosp Nottingham England NG5 1PB y Hosp, Nottingham NG5 1PB, England Univ Paris 05, Cochin Hosp, Dept Rheumatol, F-75014 Paris, France Univ Paris 05 Paris France F-75014 Dept Rheumatol, F-75014 Paris, France
Titolo Testata:
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
fascicolo: 4, volume: 15, anno: 2001,
pagine: 517 - 525
SICI:
1521-6942(200110)15:4<517:EMOOPI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACEBO-CONTROLLED TRIAL; KNEE OSTEOARTHRITIS; CLINICAL-TRIALS; MEDICAL-MANAGEMENT; STANDING COMMITTEE; HIP; GUIDELINES; EXERCISE; JOINT; RECOMMENDATIONS;
Keywords:
management guidelines; nature of OA; study design issues; generalizability of data; effect size; NNT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Doherty, M City Hosp, Clin Sci Bldg, Nottingham NG5 1PB, England City HospClin Sci Bldg Nottingham England NG5 1PB PB, England
Citazione:
M. Doherty e M. Dougados, "Evidence-based management of osteoarthritis: practical issues relating to the data", BEST PR R C, 15(4), 2001, pp. 517-525

Abstract

Osteoarthritis (OA) is a major cause of pain and disability in the elderly. The perspective of OA as a dynamic process triggered by diverse insults is increasingly accepted. Objectives of management are patient education, relief of pain, optimization of function and modification of the OA process. Management should be individualized and should take into account factors relating to the person as well as the OA joint. There is a reasonable evidence base for several key elements of management. Recent review of the research evidence shows a skewed distribution in favour of drugs, particularly NSAIDs, and important gaps in clinically relevant knowledge. The restricted generalizability of the research data could be improved by improvements in study design and methods of reporting. Current published guidelines on management of OA are critically reviewed and compared.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 16:03:34