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Titolo:
Current methods of testing for human papillomavirus
Autore:
Davies, P; Kornegay, J; Iftner, T;
Indirizzi:
BMI Hlth Serv, Adv Diagnost Ctr, London NW10 6RF, England BMI Hlth Serv London England NW10 6RF nost Ctr, London NW10 6RF, England Roche Mol Syst Inc, Alameda, CA 94501 USA Roche Mol Syst Inc Alameda CA USA 94501 l Syst Inc, Alameda, CA 94501 USA Univ Klinikum Tuebingen, Sekt Expt Virol, D-72076 Tubingen, Germany Univ Klinikum Tuebingen Tubingen Germany D-72076 72076 Tubingen, Germany
Titolo Testata:
BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY
fascicolo: 5, volume: 15, anno: 2001,
pagine: 677 - 700
SICI:
1521-6934(200110)15:5<677:CMOTFH>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-RISK HPV; CERVICAL INTRAEPITHELIAL NEOPLASIA; POLYMERASE-CHAIN-REACTION; NESTED CASE-CONTROL; HYBRID-CAPTURE-II; CARCINOMA IN-SITU; LINE PROBE ASSAY; 14 HIGH-RISK; BROAD-SPECTRUM; CLINICAL-EVALUATION;
Keywords:
cervix neoplasms/*diagnosis; papovaviridae infection/*diagnosis; tumour virus infections/*diagnosis; DNA; viral/analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Davies, P BMI Hlth Serv, Adv Diagnost Ctr, Cumberland House,Victoria Rd, London NW106RF, England BMI Hlth Serv Cumberland House,Victoria Rd London England NW10 6RF
Citazione:
P. Davies et al., "Current methods of testing for human papillomavirus", BEST P R CL, 15(5), 2001, pp. 677-700

Abstract

Human papillomavirus DNA testing is gaining wider acceptance, yet the majority of testing is still undertaken in the research setting using protocolsthat are unsuitable for clinical diagnostic laboratories. Large-scale clinical human papillomavirus DNA testing is likely to be introduced as an adjunct to cervical cytology, so the cytology laboratory is an appropriate place for it to be undertaken. This poses a challenge for any human papillomavirus DNA test since it will be performed by technicians not specifically trained in virology or molecular biology, and will need to produce consistently reliable results in this setting. This is only realistically possible with a standardized and quality-controlled, commercially produced human papillomavirus DNA test. There is currently only one such commercially available assay, although there are a number of research-based tests that could logically lead to additional commercial products. The technological basis of these assays, together with available performance data, is reviewed in this chapter and the clinical utility of the tests is evaluated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 11:56:03