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Titolo:
Solitary schwannoma of the colon: Report of two cases
Autore:
Inagawa, S; Hori, M; Shimazaki, J; Matsumoto, S; Ishii, H; Itabashi, M; Adachi, S; Kawamoto, T; Fukao, K;
Indirizzi:
Ibaraki Prefectural Cent Hosp & Canc Ctr, Dept Pathol, Tsukuba, Ibaraki 3058558, Japan Ibaraki Prefectural Cent Hosp & Canc Ctr Tsukuba Ibaraki Japan 3058558 an Ibaraki Prefectural Cent Hosp & Canc Ctr, Dept Internal Med, Tsukuba, Ibaraki 3058558, Japan Ibaraki Prefectural Cent Hosp & Canc Ctr Tsukuba Ibaraki Japan 3058558 an Ibaraki Prefectural Cent Hosp & Canc Ctr, Dept Surg, Tsukuba, Ibaraki 3058558, Japan Ibaraki Prefectural Cent Hosp & Canc Ctr Tsukuba Ibaraki Japan 3058558 an Univ Tsukuba, Inst Clin Med, Dept Surg, Tsukuba, Ibaraki, Japan Univ Tsukuba Tsukuba Ibaraki Japan d, Dept Surg, Tsukuba, Ibaraki, Japan
Titolo Testata:
SURGERY TODAY
fascicolo: 9, volume: 31, anno: 2001,
pagine: 833 - 838
SICI:
0941-1291(2001)31:9<833:SSOTCR>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
GASTROINTESTINAL STROMAL TUMORS; AUTONOMIC NERVE TUMORS; CELLULAR SCHWANNOMA; BENIGN SCHWANNOMA; SHEATH TUMORS; TRACT;
Keywords:
schwannoma; neurilemmoma; S-100 protein; colon;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Inagawa, S Ibaraki Prefectural Cent Hosp & Canc Ctr, Dept Pathol, 1-3-1 Amakubo, Tsukuba, Ibaraki 3058558, Japan Ibaraki Prefectural Cent Hosp & CancCtr 1-3-1 Amakubo Tsukuba Ibaraki Japan 3058558
Citazione:
S. Inagawa et al., "Solitary schwannoma of the colon: Report of two cases", SURG TODAY, 31(9), 2001, pp. 833-838

Abstract

Some patients with gastrointestinal schwannoma (GIS) have been previously reported in the literature. However, GIS of the colon is quite rare. In addition, it is sometimes difficult to differentiate neurogenic tumors from other soft tissue tumors. We herein describe two cases of schwannoma of the colon, while also reviewing the relevant Japanese literature. The first case, a 73-year-old woman underwent a sigmoidectomy with lymph node dissection following the diagnosis of submucosal tumor. In the second case, a submucosal tumor was located in the cecum of a 44-year-old man. An endoscopic tumorresection was performed in the second case. The resected tumors measured 3.6 and 1.0 cm in maximal diameter, respectively. Microscopically, the tumors consisted predominantly of spindle-shaped cells that proliferated in an interlaced fashion. Mitosis was rarely seen in these tumors. Immunohistochemically, the tumor cells were strongly positive for S-100 protein, weakly positive for glial fibrillary acidic protein, and negative for CD34, alpha -smooth-muscle actin, and cytokeratin (CAM 5.2) in both cases. The tumors in the two cases were both diagnosed to be benign schwannoma of the colon. In general, schwannoma of the gastrointestinal tract is considered to be benign and should therefore be distinguished from other spindle-cell tumors or malignancies. Once diagnosed as schwannoma, extensive surgery should be avoided. Actually, such patients tend to show a good postoperative course with no evidence of recurrence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 19:55:16