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Titolo:
THE VALUE OF TRANSFORMED LYMPHOCYTE COUNT IN SUBCLASSIFICATION OF NON-HODGKINS-LYMPHOMA BY FINE-NEEDLE ASPIRATION
Autore:
YOUNG NA; ALSALEEM TI; ALSALEEM Z; EHYA H; SMITH MR;
Indirizzi:
FOX CHASE CANC CTR,DEPT PATHOL,7701 BURHOLME AVE PHILADELPHIA PA 19111 FOX CHASE CANC CTR,DEPT MED ONCOL PHILADELPHIA PA 19111
Titolo Testata:
American journal of clinical pathology
fascicolo: 2, volume: 108, anno: 1997,
pagine: 143 - 151
SICI:
0002-9173(1997)108:2<143:TVOTLC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
MALIGNANT-LYMPHOMA; DIAGNOSIS; CYTOLOGY; BIOPSY; LIMITATIONS; MANAGEMENT; NEOPLASMS;
Keywords:
LYMPHOMA; CLASSIFICATION; DIAGNOSIS; PATHOLOGY NEEDLE BIOPSY; FINE-NEEDLE ASPIRATION; LYMPHOCYTE TRANSFORMATION; FLOW CYTOMETRY; CYTOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
N.A. Young et al., "THE VALUE OF TRANSFORMED LYMPHOCYTE COUNT IN SUBCLASSIFICATION OF NON-HODGKINS-LYMPHOMA BY FINE-NEEDLE ASPIRATION", American journal of clinical pathology, 108(2), 1997, pp. 143-151

Abstract

No established criteria exist for predicting lymphoma grade or transformation in cytologic material. We counted transformed lymphocytes in fine-needle aspiration (FNA) biopsy specimens to determine whether thepercentage of these cells in the smear could predict the histologic grade, the biologic behavior, or both. The percentage of transformed lymphocytes out of total lymphoid cells was determined on Papanicolaou-stained smears. Afterward, a cytodiagnosis was based on clinical information available at the time of the FNA, cytomorphologic data, and flowcytometry data. Results were correlated with results of examination of the surgical biopsy specimen, clinical behavior of the lymphoma, or both. The percentage of transformed lymphocytes was 10% or less in alllow-grade or indolent lymphomas. Aspirates with transformed lymphocyte counts of 20% or greater were aggressive lymphomas. We also report our experience in the diagnosis of non-Hodgkin's lymphoma by FNA using cytomorphologic examination and immunophenotyping by flow cytometry ata cancer referral hospital. This is a preliminary study, and larger series may help establish the ranges of transformed lymphocyte counts that correlate with the lymphoma subtype.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 00:24:48