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Titolo:
HYPERBARIC-OXYGEN IN THE TREATMENT OF ACUTE ISCHEMIC STROKE - AN UNSETTLED ISSUE
Autore:
NIGHOGHOSSIAN N; TROUILLAS P;
Indirizzi:
HOP NEUROL,SERV NEUROL PR PAUL TROUILLAS,URGENCES NEUROVASC & CTR RECH ATAXIE,59 BD PINEL F-69003 LYON FRANCE CEREBROVASC DIS & ATAXIA RES CTR,DEPT NEUROL LYON FRANCE
Titolo Testata:
Journal of the neurological sciences
fascicolo: 1, volume: 150, anno: 1997,
pagine: 27 - 31
SICI:
0022-510X(1997)150:1<27:HITTOA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
MIDDLE CEREBRAL-ARTERY; LIPID-PEROXIDATION; BLOOD-FLOW; BRAIN; THERAPY; METABOLISM; VELOCITY; PENUMBRA; PRESSURE; GERBILS;
Keywords:
ISCHEMIC STROKE; HYPERBARIC OXYGEN; EFFICIENCY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
50
Recensione:
Indirizzi per estratti:
Citazione:
N. Nighoghossian e P. Trouillas, "HYPERBARIC-OXYGEN IN THE TREATMENT OF ACUTE ISCHEMIC STROKE - AN UNSETTLED ISSUE", Journal of the neurological sciences, 150(1), 1997, pp. 27-31

Abstract

Therapy for acute ischemic stroke can be approached in two basic ways: first, by an attempt to restore or improve blood flow in an occludedvascular territory and, second, via therapy directed at the cellular and metabolic targets. As local anoxia and energy failure are the initiating cellular stage in ischemia, the inhalation of oxygen at increased atmospheric pressures might be effective. Treatment of acute focal cerebral ischemia with hyperbaric oxygen (HBO) has been reported in animals and humans. In general, the results of research in animals have suggested a promising role for the use of HBO. More than 400 cases of human ischemic stroke treated with HBO have been reported. In about half of the cases, improvement in status has been claimed on clinical orelectroencephalographic grounds. In fact, the effectiveness of HBO inmost disease processes other than carbon monoxide poisoning and decompression sickness is a subject of major ongoing debate. This short review will attempt: (1) to recall some early experiments involving HBO in the treatment of acute ischemia; (2) to point out some conflicting results regarding the role of HBO on cellular and metabolic disorders; and (3) to determine the possibility of a future role for HBO therapy in acute ischemic stroke. (C) 1997 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:59:42