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Titolo:
Synthetic and biological studies on coumarin hydrazone derivatives
Autore:
El-Sayed, AM; Abd Allah, OA;
Indirizzi:
S Valley Univ, Fac Sci, Dept Chem, Sohag, Egypt S Valley Univ Sohag Egypt Valley Univ, Fac Sci, Dept Chem, Sohag, Egypt
Titolo Testata:
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
, volume: 170, anno: 2001,
pagine: 75 - 86
SICI:
1042-6507(2001)170:<75:SABSOC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Keywords:
coumarin hydrazone; isothiocyanate; ylidenenitriles; biological activity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: El-Sayed, AM S Valley Univ, Fac Sci, Dept Chem, Sohag, Egypt S Valley Univ Sohag Egypt Fac Sci, Dept Chem, Sohag, Egypt
Citazione:
A.M. El-Sayed e O.A. Abd Allah, "Synthetic and biological studies on coumarin hydrazone derivatives", PHOSPHOR SU, 170, 2001, pp. 75-86

Abstract

The reaction of both of coumarin and 6-nitrocoumarin hydrazones (1,4) withalkyl(aryl)isothiocyanate afforded the corresponding 3-N[alkyl(aryl)thioamido] coumarins 3(a-d) or benzopyrano[2,3-c]pyrazole-3-thione derivatives 6(a-d), respectively, Compounds (3(a-d)) were used as key intermediates for the preparation of benzopyrano-pyridine derivatives (7(a-d) & 10(a)) or benzopyranoazepine derivatives 8(a,c) & 12(a-d) through the reaction with different acyl halides or ethoxymethylenemalononitriles and subsequent cyclization. Biological activity of some new compounds against Gram +ve and Gram -vewere given.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:23:33