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Titolo:
The melanosome: Membrane dynamics in black and white
Autore:
Marks, MS; Seabra, MC;
Indirizzi:
Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 & Lab Med, Philadelphia, PA 19104 USA Univ London Imperial Coll Sci Technol & Med, Fac Med, Div Biomed Sci, London SW7 2AZ, England Univ London Imperial Coll Sci Technol & Med London England SW7 2AZ gland
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 10, volume: 2, anno: 2001,
pagine: 738 - 748
SICI:
1471-0072(200110)2:10<738:TMMDIB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
HERMANSKY-PUDLAK-SYNDROME; CHEDIAK-HIGASHI-SYNDROME; BROWN LOCUS PROTEIN; DI-LEUCINE; MYOSIN-V; ENDOSOMAL TRAFFICKING; AP-3 ADAPTER; MULTIVESICULAR BODIES; CULTURED MELANOCYTES; ORGANELLE TRANSPORT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
118
Recensione:
Indirizzi per estratti:
Indirizzo: Marks, MS Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 Philadelphia, PA 19104 USA
Citazione:
M.S. Marks e M.C. Seabra, "The melanosome: Membrane dynamics in black and white", NAT REV MOL, 2(10), 2001, pp. 738-748

Abstract

Melanosomes are morphologically and functionally unique organelles within which melanin pigments are synthesized and stored. Melanosomes share some characteristics with lysosomes, but can be distinguished from them in many ways. The biogenesis and intracellular movement of melanosomes and related organelles are disrupted in several genetic disorders in mice and humans. The recent characterization of genes defective in these diseases has reinvigorated interest in the melanosome as a model system for understanding the molecular mechanisms that underlie intracellular membrane dynamics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 13:41:25