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Titolo:
Specific antibody levels and antigenic recognition of Wistar rats inoculated with distinct isolates of Trypanosoma evansi
Autore:
Queiroz, AO; Legey, AP; Xavier, SCC; Jansen, AM;
Indirizzi:
Fiocruz MS, Inst Oswaldo Cruz, Dept Protozool, BR-21045900 Rio De Janeiro,Brazil Fiocruz MS Rio De Janeiro Brazil BR-21045900 BC900 Rio De Janeiro,Brazil
Titolo Testata:
MEMORIAS DO INSTITUTO OSWALDO CRUZ
fascicolo: 7, volume: 96, anno: 2001,
pagine: 965 - 972
SICI:
0074-0276(200110)96:7<965:SALAAR>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
KINETOPLAST DNA; MATO-GROSSO; INFECTION; RABBITS; CATTLE; BRAZIL; STOCKS; SUSCEPTIBILITY; EQUIPERDUM; CAPYBARAS;
Keywords:
Trypanosoma evansi; Wistar rats; antigenic recognition; indirect fluorescent antibody test;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Jansen, AM Fiocruz MS, Inst Oswaldo Cruz, Dept Protozool, Av Brasil 4365, BR-21045900Rio De Janeiro, Brazil Fiocruz MS Av Brasil 4365 Rio De JaneiroBrazil BR-21045900 BC
Citazione:
A.O. Queiroz et al., "Specific antibody levels and antigenic recognition of Wistar rats inoculated with distinct isolates of Trypanosoma evansi", MEM I OSW C, 96(7), 2001, pp. 965-972

Abstract

"Mal de Cadeiras", an enzootic disease caused by Trypanosoma evansi, is one of the most important trypanosomiases in the Brazilian Pantanal region. The disease affects mainly horses, which are widely used in extensive cattleproduction, an activity of greatest economical significance for the region. The parasite also infects sylvan (coatis and capybaras) and domestic (dogs) animals, respectively considered wild and domestic reservoirs of T. evansi. For a better understanding of the interaction of T. evansi with its rodent host, we evaluated the differences in the specific antibody level patterns and in the parasitic peptides recognition patterns of experimentally infected Wistar rats. The rats experimentally infected with T. evansi isolates obtained from coatis, dogs and horses were submitted to indirect immunofluorescence test (IgM e IgG) and Western blotting. The serological titers for IgM and IgG ranged between 1:40 and 1:160. The most recognized polypeptide profiles were in a range of 17 and 74 kDa. Our data suggest that the humoral immune response in Wistar rats is not sufficient for granting an effective control of T. evansi infections.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 18:35:26