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Titolo:
Ethical considerations and rationale of adult-to-adult living donor liver transplantation
Autore:
Malago, M; Testa, G; Marcos, A; Fung, JJ; Siegler, M; Cronin, DC; Broelsch, CE;
Indirizzi:
Univ Essen Gesamthsch Klinikum, Klin & Poliklin Allgemein & Transplantationschiru, Operat Zentrum 2, D-45122 Essen, Germany Univ Essen Gesamthsch Klinikum Essen Germany D-45122 5122 Essen, Germany Univ Rochester, Div Solid Organ Transplantat, Dept Surg, Rochester, NY 14627 USA Univ Rochester Rochester NY USA 14627 Dept Surg, Rochester, NY 14627 USA Univ Pittsburgh, Med Ctr, Pittsburgh, PA 15260 USA Univ Pittsburgh Pittsburgh PA USA 15260 Med Ctr, Pittsburgh, PA 15260 USA Univ Chicago, Maclean Ctr Med Eth, Chicago, IL 60637 USA Univ Chicago Chicago IL USA 60637 lean Ctr Med Eth, Chicago, IL 60637 USA Univ Chicago, Dept Surg, Sect Transplantat, Chicago, IL 60637 USA Univ Chicago Chicago IL USA 60637 ect Transplantat, Chicago, IL 60637 USA
Titolo Testata:
LIVER TRANSPLANTATION
fascicolo: 10, volume: 7, anno: 2001,
pagine: 921 - 927
SICI:
1527-6465(200110)7:10<921:ECAROA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPLIT-LIVER; SURGICAL TECHNIQUES; HOSPITAL VOLUME; SMALL CENTERS; EXPERIENCE; MORTALITY; PRACTICABILITY; PERSPECTIVES; CHILDREN; EFFICACY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Malago, M Univ Essen Gesamthsch Klinikum, Klin & Poliklin Allgemein & Transplantationschiru, Operat Zentrum 2, Hufelandstr 55, D-45122 Essen, GermanyUniv Essen Gesamthsch Klinikum Hufelandstr 55 Essen Germany D-45122
Citazione:
M. Malago et al., "Ethical considerations and rationale of adult-to-adult living donor liver transplantation", LIVER TRANS, 7(10), 2001, pp. 921-927

Abstract

Adult-to-adult living donor liver transplantation (ALDLT) is a reality, shortly after its introduction into clinical practice, it is being performed in approximately 50 centers throughout the United States and Europe. The quick development of ALDLT and some deaths among donors repropose old ethicaldilemmas and confront the transplant community with new urgent problems. To minimize risks for recipients and, especially, donors, two key questions are addressed: (1) who can or should perform the procedure, and (2) what patient should undergo the procedure. The high risks taken by live donors undergoing a hemihepatectomy seem to be justified by the steadily increasing mortality of adult recipients waiting for transplantation. A comprehensive consent procedure is at the base of responsible decision making for both donors and recipients. In adherence to basic medical criteria, the autonomy ofdecision of donors and recipients, may allow the extension of indications to patients not suitable to undergo transplantation with cadaveric grafts. The broadening of indications is appropriate only in centers with adequate experience and proven expertise in ALDLT. The medical community faces the duty of regulating ALDLT before external influences force undesired policy changes, particularly if not based on medical grounds. Individual centers and patients are ultimately responsible for the correct use of LDLT.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 09:49:30