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Titolo:
The "privileged" liver and hepatic tolerogenicity
Autore:
Starzl, TE;
Indirizzi:
Thomas E Starzl Transplantat Inst, Falk Clin, Pittsburgh, PA 15213 USA Thomas E Starzl Transplantat Inst Pittsburgh PA USA 15213 h, PA 15213 USA
Titolo Testata:
LIVER TRANSPLANTATION
fascicolo: 10, volume: 7, anno: 2001,
pagine: 918 - 920
SICI:
1527-6465(200110)7:10<918:T"LAHT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENAL-ALLOGRAFTS; GRAFT ACCEPTANCE; CELL-MIGRATION; Y-CHROMOSOME; TRANSPLANTATION; ANTIGENS; HYBRIDIZATION; ANTIBODIES; CHIMERISM; TOLERANCE;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Starzl, TE Thomas E Starzl Transplantat Inst, Falk Clin, 3601 5th Ave, Pittsburgh, PA15213 USA Thomas E Starzl Transplantat Inst 3601 5th Ave Pittsburgh PA USA 15213
Citazione:
T.E. Starzl, "The "privileged" liver and hepatic tolerogenicity", LIVER TRANS, 7(10), 2001, pp. 918-920

Abstract

The mechanism underlying the imunological advantage of hepatic allografts relative to other organs is incompletely understood. We used molecular probes for the repetitive units on the Y chromosome, to identify an increasing number of male liver venous endothelial cells in needle biopsy samples of men who received female donor liver grafts. We have also shown repopulation of liver endothelium by bone marrow derived cells in a male to female mousebone marrow transplant model. We conclude that the liver has unique venousendothelium characterized by turnover and replacement by bone marrow derived cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 22:27:04