Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Soy isoflavones - Benefits and risks from nature's selective estrogen receptor modulators (SERMs)
Autore:
Setchell, KDR;
Indirizzi:
Childrens Hosp, Med Ctr, Dept Pediat, Cincinnati, OH 45229 USA Childrens Hosp Cincinnati OH USA 45229 t Pediat, Cincinnati, OH 45229 USA
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
fascicolo: 5, volume: 20, anno: 2001, supplemento:, S
pagine: 354S - 362S
SICI:
0731-5724(200110)20:5<354S:SI-BAR>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOW-DENSITY-LIPOPROTEIN; SYSTEMIC ARTERIAL COMPLIANCE; BETA-GLUCOSIDASE ACTIVITY; NON-STEROIDAL ESTROGEN; BONE LOSS; POSTMENOPAUSAL WOMEN; BREAST-CANCER; HUMAN HEALTH; HUMAN-URINE; DIETARY PHYTOESTROGENS;
Keywords:
soy isoflavones; phytoestrogens; pharmacokinetics; phytoprotectants;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
121
Recensione:
Indirizzi per estratti:
Indirizzo: Setchell, KDR Childrens Hosp, Med Ctr, Dept Pediat, 3333 Burnet Ave, Cincinnati, OH 45229 USA Childrens Hosp 3333 Burnet Ave Cincinnati OH USA 45229 9 USA
Citazione:
K.D.R. Setchell, "Soy isoflavones - Benefits and risks from nature's selective estrogen receptor modulators (SERMs)", J AM COL N, 20(5), 2001, pp. 354S-362S

Abstract

Phytoestrogens have become one of the more topical areas of interest in clinical nutrition. These non-nutrient bioactive compounds are ubiquitous to the plant kingdom and possess a wide range of biological properties that contribute to the many different health-related benefits reported for soy foods and flaxseeds-two of the most abundant dietary sources of phytoestrogens. Reviewed is the recent knowledge related to their pharmacokinetics and clinical effects. focusing mainly on isoflavones that are found in high concentrations in soy foods. Arguments are made for considering soy isoflavones as natural selective estrogen receptor modulators (SERMs) based upon recentdata of their conformational binding to estrogen receptors. Rebuttal is made to several key and important issues related to the recent concerns aboutthe safety of soy and its constituent isoflavones. This article is not intended to be a comprehensive review of the literature but merely highlight recent research with key historical perspectives.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:11:46