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Titolo:
The accuracy of serum interleukin-6 and tumour necrosis factor as markers for ovarian torsion
Autore:
Cohen, SB; Wattiez, A; Stockheim, D; Seidman, DS; Lidor, AL; Mashiach, S; Goldenberg, M;
Indirizzi:
Sackler Sch Med, Dept Obstet & Gynecol, J Buchman Matern Ctr, Sheba Med Ctr, IL-52621 Tel Hashomer, Israel Sackler Sch Med Tel Hashomer Israel IL-52621 -52621 Tel Hashomer, Israel Tel Aviv Univ, Sheba Med Ctr, Dept Obstet & Gynecol, J Buchman Matern Ctr,Tel Hashomer, Israel Tel Aviv Univ Tel Hashomer Israel chman Matern Ctr,Tel Hashomer, Israel Polyclin Hotel Dieu, Dept Obstet Gynecol & Reprod Med, Clermont Ferrand, France Polyclin Hotel Dieu Clermont Ferrand France d, Clermont Ferrand, France
Titolo Testata:
HUMAN REPRODUCTION
fascicolo: 10, volume: 16, anno: 2001,
pagine: 2195 - 2197
SICI:
0268-1161(200110)16:10<2195:TAOSIA>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIAGNOSIS;
Keywords:
interleukin-6; markers; ovarian torsion; tumour necrosis factor-alpha;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Cohen, SB Sackler Sch Med, Dept Obstet & Gynecol, J Buchman Matern Ctr, Sheba Med Ctr, IL-52621 Tel Hashomer, Israel Sackler Sch Med Tel Hashomer Israel IL-52621 Hashomer, Israel
Citazione:
S.B. Cohen et al., "The accuracy of serum interleukin-6 and tumour necrosis factor as markers for ovarian torsion", HUM REPR, 16(10), 2001, pp. 2195-2197

Abstract

BACKGROUND: The aim of this study was to investigate a possible role for interleukin-6 (IL-6) and tumour necrosis factor (TNF-alpha) as pre-operativemarkers for the diagnosis of ovarian torsion. METHODS: Twenty consecutive patients admitted to the gynaecological emergency room with suspected clinical diagnosis of ovarian torsion were prospectively assigned to the study. Blood samples were drawn pre-operatively and examined for serum concentrations of IL-6 and TNF-alpha. Surgeons were blinded to laboratory results prior to laparoscopy. RESULTS: The pre-operative diagnosis of ovarian torsion was confirmed during an urgent diagnostic laparoscopy in 8 (40%) patients. The surgical diagnosis among the remaining 12 patients was a large ovarian cyst not in torsion. In six out of eight (75.0%) patients with ovarian torsion serum IL-6 concentrations were elevated. None of the 12 patients withouttorsion had elevated serum IL-6 concentrations. This difference was statistically significant (P < 0.001). There was no significant difference in theproportion of women with elevated serum TNF-alpha concentrations, two of eight (25.0%) patients with torsion and four of 12 (33.3%) control cases. CONCLUSIONS: Elevated serum IL-6 concentrations, but not serum TNF-alpha concentrations, were significantly associated with the occurrence of ovarian torsion. In patients with vague clinical signs of ovarian torsion, serum IL-6might help to distinguish which patients should undergo diagnostic laparoscopy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:38:27