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Titolo:
A joint analysis of asthma affection status and IgE levels in multiple data sets collected for asthma
Autore:
Markianos, K; Carlson, S; Gibbs, M; Kruglyak, L;
Indirizzi:
Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr Seattle WA USA 98109 , Seattle, WA 98109 USA Howard Hughes Med Inst, Seattle, WA USA Howard Hughes Med Inst Seattle WAUSA d Hughes Med Inst, Seattle, WA USA
Titolo Testata:
GENETIC EPIDEMIOLOGY
, volume: 21, anno: 2001, supplemento:, 1
pagine: S148 - S153
SICI:
0741-0395(2001)21:<S148:AJAOAA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
QUANTITATIVE TRAIT LOCI; GENOME-WIDE SEARCH; LINKAGE ANALYSIS; PEDIGREES;
Keywords:
linkage; lod score; nonparametric linkage; quantitative trait locus (QTL);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Markianos, K Fred Hutchinson Canc Res Ctr, 1100 Fairview Ave N,D4100,POB 19024, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr 1100 Fairview Ave N,D4100,POB 19024 Seattle WA USA 98109
Citazione:
K. Markianos et al., "A joint analysis of asthma affection status and IgE levels in multiple data sets collected for asthma", GENET EPID, 21, 2001, pp. S148-S153

Abstract

We present a joint linkage analysis of eight data sets collected for asthma. Three of the data sets are full genome scans, while the remaining five concentrate on a 40-cM region on chromosome 5. We perform the analysis usingone qualitative and one quantitative phenotype: asthma status and IgE level. Considering all data sets simultaneously, we do not find evidence for linkage to asthma affection status beyond the level expected to occur by chance twice per genome scan. In contrast, we observe significant linkage to IgE level on chromosome 6. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 02:40:48