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Titolo:
On the detection of linkage in multiple data sets: A comparison of variousstatistical approaches
Autore:
Van Eerdewegh, P; Dowd, M; Dupuis, J; Falls, K; Hayward, B; Santangelo, SL;
Indirizzi:
Genome Therapeut Corp, Waltham, MA 02453 USA Genome Therapeut Corp Waltham MA USA 02453 ut Corp, Waltham, MA 02453 USA Harvard Univ, Sch Med, Boston, MA USA Harvard Univ Boston MA USAHarvard Univ, Sch Med, Boston, MA USA Tufts Univ, Sch Med, Boston, MA 02111 USA Tufts Univ Boston MA USA 02111Tufts Univ, Sch Med, Boston, MA 02111 USA Harvard Univ, Sch Publ Hlth, Boston, MA 02138 USA Harvard Univ Boston MA USA 02138 niv, Sch Publ Hlth, Boston, MA 02138 USA
Titolo Testata:
GENETIC EPIDEMIOLOGY
, volume: 21, anno: 2001, supplemento:, 1
pagine: S67 - S72
SICI:
0741-0395(2001)21:<S67:OTDOLI>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROBABILITY;
Keywords:
asthma; heterogeneity lod score; posterior probability of linkage;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Van Eerdewegh, P Genome Therapeut Corp, 100 Beaver St, Waltham, MA 02453 USA Genome Therapeut Corp 100 Beaver St Waltham MA USA 02453
Citazione:
P. Van Eerdewegh et al., "On the detection of linkage in multiple data sets: A comparison of variousstatistical approaches", GENET EPID, 21, 2001, pp. S67-S72

Abstract

We contrast the pooling of multiple data sets with the compound HLOD (HLOD-C) and the posterior probability of linkage (PPL), two approaches that have been shown to have more power in the presence of genetic heterogeneity. We also propose and evaluate several multipoint extensions. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 19:52:11