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Titolo:
Pulmonary lobectomy for lung cancer: a prospective study to compare patients with forced expiratory volume in 1 s more or less than 80% of predicted
Autore:
Santambrogio, L; Nosotti, M; Baisi, A; Ronzoni, G; Bellaviti, N; Rosso, L;
Indirizzi:
Osped Maggiore Policlin, IRCCS, Thorac Surg Unit, I-20122 Milan, Italy Osped Maggiore Policlin Milan Italy I-20122 g Unit, I-20122 Milan, Italy
Titolo Testata:
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
fascicolo: 4, volume: 20, anno: 2001,
pagine: 684 - 687
SICI:
1010-7940(200110)20:4<684:PLFLCA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMPHYSEMA; RESECTION; IMPROVEMENT; REDUCTION; MORTALITY; DISEASE; RISK;
Keywords:
non-small cell lung cancers; surgery; obstructive lung disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Nosotti, M Osped Maggiore Policlin, IRCCS, Thorac Surg Unit, Via F Sforza 35, I-20122Milan, Italy Osped Maggiore Policlin Via F Sforza 35 Milan Italy I-20122 ly
Citazione:
L. Santambrogio et al., "Pulmonary lobectomy for lung cancer: a prospective study to compare patients with forced expiratory volume in 1 s more or less than 80% of predicted", EUR J CAR-T, 20(4), 2001, pp. 684-687

Abstract

Objective: To compare post-operative course, lung function and survival oflung cancer patients with a forced expiratory volume in Is FEV1) more or less than 80% of predicted submitted to lobectomy. Methods: The data of patients undergoing lobectomy for non small cell carcinoma at the Thoracic Surgery Unit of the Ospedale Maggiore Policlinico of Milan, Italy, were prospectively collected. Inclusion criteria were a radical resectable tumor with size less than 2.5 cm, negative mediastinal nodes, capability to complete pulmonary function tests, Exclusion criteria were FEV1 < 40% of predicted, pre- or post-operative chemo or radiotherapy, lobe to be resected receiving more than 30% of the perfusion. incapacity to quit smoking. Results: Eighty-eight patients entered the study and were divided into two groups accordingto their FEV1%: 45 patients were included in control group (mean FEV1: 92.2%) and 42 in chronic obstructive pulmonary disease group (mean FEV1: 64.2%). Post-operative complications, operative mortality and actuarial survivalwere the same in the 2 groups. Six months after lobectomy, the mean changes in FEV1 were - 14.9% for first group and -3.2% for second group (P < 0.001). Conclusion: Lobectomy for cancer can be performed successfully also in selected patients with chronic obstructive pulmonary disease. Post-operative course and survival of these patients is not different from that of patients with normal FEV1, on the contrary, patients with low FEV I may lose less pulmonary function or even mend it. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 20:13:29