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Titolo:
Hippocampal H-1-MRSI in ecstasy users
Autore:
Obergriesser, T; Ende, G; Braus, DF; Henn, FA;
Indirizzi:
Cent Inst Mental Hlth, NMR Res, D-68072 Mannheim, Germany Cent Inst MentalHlth Mannheim Germany D-68072 D-68072 Mannheim, Germany
Titolo Testata:
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
fascicolo: 3, volume: 251, anno: 2001,
pagine: 114 - 116
SICI:
0940-1334(200106)251:3<114:HHIEU>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUTOMATED SPECTRAL-ANALYSIS; TEMPORAL-LOBE EPILEPSY; 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA; METABOLITE CHANGES; PROTON; SPECTROSCOPY; NEURONS; HUMANS; MRS;
Keywords:
3,4-methylenedioxymethamphetamine; hippocampus; nuclear magnetic resonance;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Obergriesser, T Cent Inst Mental Hlth, NMR Res, POB 122120, D-68072 Mannheim, Germany Cent Inst Mental Hlth POB 122120 Mannheim Germany D-68072
Citazione:
T. Obergriesser et al., "Hippocampal H-1-MRSI in ecstasy users", EUR ARCH PS, 251(3), 2001, pp. 114-116

Abstract

In recent years the illicit drug ecstasy (MDMA, 3,4-methylenedioxymethamphetamine) has come into widespread use among young people. Despite clear evidence for the neurotoxic potential of MDMA in animals, corresponding evidence in humans is limited to indirect findings. In an exploratory study we compared the hippocampal H-1-MRSI (magnetic resonance spectroscopic imaging) spectra, of five MDMA users with those of controls with no history of substance abuse. Although H-1-MRSI is, sensitive in detecting alterations in neuronal viability in association with diseases leading to neuronal degeneration, we were not able to demonstrate any differences in hippocampal H-1-MRSIbetween MDMA users and controls.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:51:14